{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T06:23:57Z","timestamp":1773037437257,"version":"3.50.1"},"reference-count":21,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Benign papular eruption on the left leg of a 72-year-old diabetic man developed into rapidly spreading necrotizing fasciitis despite antimicrobial therapy and surgical debridements. This led to eventual amputation to control the infection. The etiological agent was a\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            isolate harboring the enterotoxin gene cluster\n            <jats:italic>seg<\/jats:italic>\n            ,\n            <jats:italic>sei<\/jats:italic>\n            ,\n            <jats:italic>sem<\/jats:italic>\n            ,\n            <jats:italic>sen<\/jats:italic>\n            , and\n            <jats:italic>seo<\/jats:italic>\n            but lacked all common toxin genes, including Panton-Valentine leukocidin.\n          <\/jats:p>","DOI":"10.1128\/jcm.01657-06","type":"journal-article","created":{"date-parts":[[2006,12,14]],"date-time":"2006-12-14T02:55:43Z","timestamp":1166064943000},"page":"668-671","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":25,"title":["Necrotizing Fasciitis Due to a Methicillin-Sensitive\n            <i>Staphylococcus aureus<\/i>\n            Isolate Harboring an Enterotoxin Gene Cluster"],"prefix":"10.1128","volume":"45","author":[{"given":"William R.","family":"Morgan","sequence":"first","affiliation":[{"name":"Department of Internal Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"Caldwell","sequence":"additional","affiliation":[{"name":"Department of Surgery"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer M.","family":"Brady","sequence":"additional","affiliation":[{"name":"Molecular Microbiology Laboratory, Marshfield Clinic Research Foundation, Marshfield, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary E.","family":"Stemper","sequence":"additional","affiliation":[{"name":"Marshfield Laboratories, Marshfield, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt D.","family":"Reed","sequence":"additional","affiliation":[{"name":"Department of Pathology, Marshfield Clinic, Marshfield, Wisconsin"},{"name":"Molecular Microbiology Laboratory, Marshfield Clinic Research Foundation, Marshfield, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay K.","family":"Shukla","sequence":"additional","affiliation":[{"name":"Molecular Microbiology Laboratory, Marshfield Clinic Research Foundation, Marshfield, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa044194"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08713-5"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.33.3.551-555.1995"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00773-06"},{"key":"e_1_3_2_6_2","first-page":"707","volume":"48","year":"1999","unstructured":"Centers for Disease Control and Prevention. 1999. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus-Minnesota and North Dakota, 1997-1999. Morb. Mortal. Wkly. Rep.48:707-710. [Online.] http:\/\/www.cdc.gov\/mmwr\/preview\/mmwrhtml\/mm4832a2.htm .","journal-title":"Morb. Mortal. Wkly. 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Chou, M. Y. Peng, and F. Y. Chang. 2005. Rapidly progressive necrotizing fasciitis caused by Staphylococcus aureus. J. Microbiol. Immunol. Infect.38:361-364.","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.11.5113-5120.2003"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042683"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.2.796-801.2005"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.8.3080-3085.2004"},{"key":"e_1_3_2_22_2","first-page":"909","volume":"23","year":"2004","unstructured":"Wong, C. H., S. H. Tan, A. Kurup, and A. B. Tan. 2004. Recurrent necrotizing fasciitis caused by methicillin-resistant Staphylococcus aureus. Eur. J. Clin. Microbiol. Infect. Dis.23:909-911.","journal-title":"Eur. J. Clin. Microbiol. Infect. 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