{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T04:25:29Z","timestamp":1790915129633,"version":"4.1.0"},"reference-count":11,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            (1-3)-\u03b2-\n            <jats:sc>d<\/jats:sc>\n            -Glucan (BG) reactivity was tested in serum samples from 28 patients with human immunodeficiency virus infection or a hematological malignancy and\n            <jats:italic>Pneumocystis jirovecii<\/jats:italic>\n            pneumonia (PCP) and 28 control patients. The sensitivity and specificity of BG detection with the Fungitell assay for PCP were 100 and 96.4%, respectively, using a cutoff value of 100 pg\/ml. Serum BG testing looks promising for the noninvasive diagnosis of PCP. Our data suggest that a higher cutoff value for the diagnosis of PCP than for the diagnosis of invasive aspergillosis or candidiasis could be used safely and will improve the specificity of the test.\n          <\/jats:p>","DOI":"10.1128\/jcm.01756-09","type":"journal-article","created":{"date-parts":[[2009,10,22]],"date-time":"2009-10-22T01:45:18Z","timestamp":1256175918000},"page":"3871-3874","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":97,"title":["Serum (1-3)-\u03b2-\n            <scp>d<\/scp>\n            -Glucan as a Tool for Diagnosis of\n            <i>Pneumocystis jirovecii<\/i>\n            Pneumonia in Patients with Human Immunodeficiency Virus Infection or Hematological Malignancy"],"prefix":"10.1128","volume":"47","author":[{"given":"Stefanie","family":"Desmet","sequence":"first","affiliation":[{"name":"Departments of Medical Diagnostic Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Van Wijngaerden","sequence":"additional","affiliation":[{"name":"General Internal Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Maertens","sequence":"additional","affiliation":[{"name":"Hematology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Verhaegen","sequence":"additional","affiliation":[{"name":"Departments of Medical Diagnostic Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Verbeken","sequence":"additional","affiliation":[{"name":"Pathology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"De Munter","sequence":"additional","affiliation":[{"name":"General Internal Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wouter","family":"Meersseman","sequence":"additional","affiliation":[{"name":"General Internal Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britt","family":"Van Meensel","sequence":"additional","affiliation":[{"name":"Departments of Medical Diagnostic Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Van Eldere","sequence":"additional","affiliation":[{"name":"Departments of Medical Diagnostic Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrien","family":"Lagrou","sequence":"additional","affiliation":[{"name":"Departments of Medical Diagnostic Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-1309"},{"key":"e_1_3_2_3_2","first-page":"1364","volume":"47","year":"2008","unstructured":"Cuetara, M. S., A. Alhambra, F. Chaves, M. D. Moragues, J. Ponton, and A. del Palacio. 2008. Use of a serum (1\u21923)-\u03b2-d-glucan assay for diagnosis and follow-up of Pneumocystis jiroveci pneumonia. Clin. Infect. Dis.47:1364-1366.","journal-title":"Clin. Infect. Dis."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/140.5.1204"},{"key":"e_1_3_2_6_2","first-page":"70","volume":"147","year":"2007","unstructured":"Marty, F. M., S. Koo, J. Bryar, and L. R. Baden. 2007. (1\u21923)\u03b2-d-Glucan assay positivity in patients with Pneumocystis (carinii) jiroveci pneumonia. Ann. Intern. Med.147:70-72.","journal-title":"Ann. Intern. 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Agents Chemother. 2005"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.01756-09","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.01756-09","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T06:44:04Z","timestamp":1646462644000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.01756-09"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["10.1128\/JCM.01756-09"],"URL":"https:\/\/doi.org\/10.1128\/jcm.01756-09","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]},"assertion":[{"value":"2009-09-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-10-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}