{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T08:18:37Z","timestamp":1785831517333,"version":"3.56.0"},"reference-count":15,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T00:00:00Z","timestamp":1582502400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2020,2,24]]},"abstract":"<jats:p>\n            The addition of toxin enzyme immunoassay (EIA) to nucleic acid amplification tests, including PCR, creates challenges in the diagnosis and management of\n            <jats:named-content content-type=\"genus-species\">Clostridioides difficile<\/jats:named-content>\n            infection (CDI). There are limited data in large cohorts, with discordant results, that is, PCR-positive\/EIA-negative (PCR\n            <jats:sup>+<\/jats:sup>\n            \/EIA\n            <jats:sup>\u2212<\/jats:sup>\n            ) results. We conducted a retrospective cohort study on all PCR\n            <jats:sup>+<\/jats:sup>\n            \/EIA\n            <jats:sup>\u2212<\/jats:sup>\n            adult inpatients and assessed CDI-related complications and clinical failure.\n          <\/jats:p>","DOI":"10.1128\/jcm.01764-19","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T12:58:47Z","timestamp":1578056327000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":33,"title":["Predictors of Clostridioides difficile Infection-Related Complications and Treatment Patterns among Nucleic Acid Amplification Test-Positive\/Toxin Enzyme Immunoassay-Negative Patients"],"prefix":"10.1128","volume":"58","author":[{"given":"Ryan","family":"Miller","sequence":"first","affiliation":[{"name":"Department of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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