{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:51:06Z","timestamp":1762865466050},"reference-count":26,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2008,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Out of 175 pneumococcal isolates from middle ear fluids, 26.3% were penicillin-resistant\n            <jats:italic>S. pneumoniae<\/jats:italic>\n            (PRSP). Serotypes 19F and 23F occurred most frequently among PRSP strains. The 7-valent pneumococcal conjugate vaccine (PCV) showed better coverage of PRSP strains (87.0%). The 7-valent PCV may reduce the prevalence of PRSP in Japan.\n          <\/jats:p>","DOI":"10.1128\/jcm.01782-08","type":"journal-article","created":{"date-parts":[[2008,10,2]],"date-time":"2008-10-02T01:50:43Z","timestamp":1222912243000},"page":"3808-3810","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":31,"title":["Serotype Distribution and Penicillin Resistance of\n            <i>Streptococcus pneumoniae<\/i>\n            Isolates from Middle Ear Fluids of Pediatric Patients with Acute Otitis Media in Japan"],"prefix":"10.1128","volume":"46","author":[{"given":"Muneki","family":"Hotomi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dewan S.","family":"Billal","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosuke","family":"Kamide","sequence":"additional","affiliation":[{"name":"Kamide ENT Clinic, Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Kanesada","sequence":"additional","affiliation":[{"name":"Nonohana Clinic, Yamaguchi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshifumi","family":"Uno","sequence":"additional","affiliation":[{"name":"Uno ENT Clinic, Okayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumiyo","family":"Kudo","sequence":"additional","affiliation":[{"name":"Chiba College of Public Health, Chiba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Kanazawa University, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Kakehata","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Hirosaki, University, Hirosaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rinya","family":"Sugita","sequence":"additional","affiliation":[{"name":"Sugita ENT Clinic, Chiba, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Ogami","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noboru","family":"Yamanaka","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-007-0510-3"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200209000-00015"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199208001-00002"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.6.2378-2384.2003"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki302"},{"key":"e_1_3_2_7_2","unstructured":"Performance standards for antimicrobial susceptibility testing; 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