{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T18:57:27Z","timestamp":1761418647741},"reference-count":50,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            There are few data about the epidemiology of community-associated methicillin-resistant\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            (CA-MRSA) among children in Israel. This study was intended to identify risk factors for CA-MRSA colonization in healthy infants, to characterize the molecular features of colonizing organisms, and to determine whether they are responsible for health care-associated (HA) infections. Nasal cultures and demographic details were collected from a cohort of healthy infants at 5 visits between the ages of 2 and 12 months. Clinical characteristics of pediatric MRSA bloodstream infections (2001 to 2006) and wound cultures collected over 6 months were also studied. Clonal structure was evaluated by multilocus sequence typing. Isolates were studied for the staphylococcal cassette chromosome\n            <jats:italic>mec<\/jats:italic>\n            (SCC\n            <jats:italic>mec<\/jats:italic>\n            ) type and for the presence of Panton-Valentine leukocidin (PVL) genes. MRSA was cultured at least once from 45 of 659 infants (346 Jewish and 313 Bedouin infants). Forty of 45 (89%) isolates were from Bedouin infants. Twenty-nine of 45 (64.4%) belonged to a new clonal complex, designated CC913, that carries SCC\n            <jats:italic>mec<\/jats:italic>\n            IV but not the PVL genes. CC913 was also isolated from 9\/14 blood cultures and 7\/8 wounds. All CC913 infections occurred in Bedouin children, and all but two were HA. In conclusion, Bedouin origin was the main risk factor for carriage of CA-MRSA. CC913 was dominant both in healthy carriers and as a cause of pediatric HA-MRSA bloodstream infections.\n          <\/jats:p>","DOI":"10.1128\/jcm.02290-08","type":"journal-article","created":{"date-parts":[[2009,12,10]],"date-time":"2009-12-10T02:40:46Z","timestamp":1260412846000},"page":"531-538","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":35,"title":["Carriage of Community-Associated Methicillin-Resistant\n            <i>Staphylococcus aureus<\/i>\n            in a Cohort of Infants in Southern Israel: Risk Factors and Molecular Features"],"prefix":"10.1128","volume":"48","author":[{"given":"Amos","family":"Adler","sequence":"first","affiliation":[{"name":"Department Clinical Microbiology and Infectious Disease, Hadassah Hebrew University Medical Center, Jerusalem"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noga","family":"Givon-Lavi","sequence":"additional","affiliation":[{"name":"Pediatric Infectious Disease Unit, Soroka Medical Center, Ben-Gurion University, Beer-Sheva, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allon E.","family":"Moses","sequence":"additional","affiliation":[{"name":"Department Clinical Microbiology and Infectious Disease, Hadassah Hebrew University Medical Center, Jerusalem"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin","family":"Block","sequence":"additional","affiliation":[{"name":"Department Clinical Microbiology and Infectious Disease, Hadassah Hebrew University Medical Center, Jerusalem"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Dagan","sequence":"additional","affiliation":[{"name":"Pediatric Infectious Disease Unit, Soroka Medical Center, Ben-Gurion University, Beer-Sheva, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/517478"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.5.2027-2032.2003"},{"key":"e_1_3_1_4_2","unstructured":"Statistical yearbook of the Negev Bedouin. 2004"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0809.020300"},{"key":"e_1_3_1_6_2","first-page":"88","volume":"52","year":"2003","unstructured":"Centers for Disease Control and Prevention. 2003. 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