{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T07:01:53Z","timestamp":1789455713770,"version":"build-2803163510"},"reference-count":18,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A matched 1:3 case-control study investigated factors predicting colistin-resistant versus colistin-susceptible KPC-producing\n            <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n            acquisition and its impact on patient outcomes. Case patients were more often admitted from other institutions (\n            <jats:italic>P =<\/jats:italic>\n            0.019) and had longer therapy with \u03b2-lactam\/\u03b2-lactamase inhibitors (\n            <jats:italic>P<\/jats:italic>\n            = 0.002) and higher overall mortality (\n            <jats:italic>P<\/jats:italic>\n            = 0.05). All 52 study isolates were clonally related, suggesting horizontal dissemination. None of these parameters independently predicted colistin resistance, which probably occurred in a susceptible KPC-KP strain that was subsequently disseminated horizontally.\n          <\/jats:p>","DOI":"10.1128\/jcm.02301-09","type":"journal-article","created":{"date-parts":[[2010,4,8]],"date-time":"2010-04-08T02:20:41Z","timestamp":1270693241000},"page":"2271-2274","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":92,"title":["Risk Factors and Outcomes Associated with Acquisition of Colistin-Resistant KPC-Producing\n            <i>Klebsiella pneumoniae<\/i>\n            : a Matched Case-Control Study"],"prefix":"10.1128","volume":"48","author":[{"given":"Olympia","family":"Zarkotou","sequence":"first","affiliation":[{"name":"Department of Microbiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spyros","family":"Pournaras","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Medical School, University of Thessaly, Larissa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelia","family":"Voulgari","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Chrysos","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanassios","family":"Prekates","sequence":"additional","affiliation":[{"name":"ICU"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dionysios","family":"Voutsinas","sequence":"additional","affiliation":[{"name":"3rd Medical Department, Tzaneio General Hospital, Piraeus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katerina","family":"Themeli-Digalaki","sequence":"additional","affiliation":[{"name":"Department of Microbiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanassios","family":"Tsakris","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.12.1430"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki175"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01114-07"},{"key":"e_1_3_1_5_2","unstructured":"Performance standards for antimicrobial susceptibility testing 2008"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1086\/600042"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp327"},{"key":"e_1_3_1_8_2","unstructured":"Breakpoint tables for interpretation of MICs and zone diameters. 2009"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00879-06"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0196-6553(88)90053-3"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1086\/648451"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00006-08"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02466-08"},{"key":"e_1_3_1_14_2","first-page":"198","volume":"58","year":"2009","unstructured":"Maltezou, H. 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