{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T10:37:25Z","timestamp":1772793445259,"version":"3.50.1"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The sensitivity of screening for methicillin-resistant\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            (MRSA) can be improved by adding other specimen sites to nares. We describe an evaluation of a new selective medium, BBL CHROMagar MRSA II (CMRSAII), for its ability to detect MRSA from different specimen types. CMRSAII is a chromogenic medium which incorporates cefoxitin for the detection of MRSA. A study was performed at four clinical laboratories with the following specimens: 1,446 respiratory, 694 stool, 1,275 skin, and 948 wound specimens and 688 blood culture bottles containing Gram-positive cocci. The recovery of MRSA on traditional culture media was compared to results with CMRSAII.\n            <jats:italic>S. aureus<\/jats:italic>\n            was tested by cefoxitin disk diffusion. CMRSAII was interpreted as positive for MRSA at 24 h (range, 18 to 28 h) based solely on the visualization of mauve-colored colonies and at 48 h (range, 36 to 52 h) based on detection of mauve colonies with subsequent confirmation as\n            <jats:italic>S. aureus<\/jats:italic>\n            (by coagulase or latex agglutination testing). MRSA was recovered more frequently on CMRSAII (89.8% at 24 h and 95.6% at 48 h) than on traditional culture plates (83.1% at 24 h and 79.8% at 48 h) for all specimen types combined (\n            <jats:italic>P<\/jats:italic>\n            &lt; 0.001). The percent sensitivities of CMRSAII at 24- and 48-h reads, respectively, were 85.5 and 92.4% for respiratory specimens, 87.9% and 98.3% for stool specimens, 88.4% and 96.1% for skin specimens, 92.1% and 94.6% for wound specimens, and 100% and 100% for positive blood cultures. The specificity was 99.8% for respiratory specimens and 100% for all others. In conclusion, CMRSAII is a reliable screening medium for multiple specimen types.\n          <\/jats:p>","DOI":"10.1128\/jcm.02374-09","type":"journal-article","created":{"date-parts":[[2010,4,15]],"date-time":"2010-04-15T01:57:18Z","timestamp":1271296638000},"page":"2223-2227","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":29,"title":["Evaluation of a New Selective Medium, BD BBL CHROMagar MRSA II, for Detection of Methicillin-Resistant\n            <i>Staphylococcus aureus<\/i>\n            in Different Specimens"],"prefix":"10.1128","volume":"48","author":[{"given":"C.","family":"Wendt","sequence":"first","affiliation":[{"name":"University Hospital Heidelberg, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. L.","family":"Havill","sequence":"additional","affiliation":[{"name":"Hospital of St. Raphael, New Haven, Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. C.","family":"Chapin","sequence":"additional","affiliation":[{"name":"Rhode Island Hospital and Brown Albert Medical School, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Boyce","sequence":"additional","affiliation":[{"name":"Hospital of St. Raphael, New Haven, Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Dickenson","sequence":"additional","affiliation":[{"name":"Rhode Island Hospital and Brown Albert Medical School, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Eigner","sequence":"additional","affiliation":[{"name":"Labor Limbach, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Schu\u0308tt","sequence":"additional","affiliation":[{"name":"University Hospital Heidelberg, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"Fahr","sequence":"additional","affiliation":[{"name":"Labor Limbach, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-008-1153-1"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2009.01.003"},{"key":"e_1_3_2_4_2","unstructured":"DART Deutsche Antibiotika-Resistenzstrategie. 2009"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/591061"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01566-08"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46981-0"},{"key":"e_1_3_2_8_2","unstructured":"Approved standard M2-A9. 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