{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:58:13Z","timestamp":1792058293008,"version":"4.4.0"},"reference-count":16,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100022110","name":"bioM\u00e9rieux","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100022110","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100022110","name":"bioM\u00e9rieux","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100022110","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100022110","name":"bioM\u00e9rieux","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100022110","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100022110","name":"bioM\u00e9rieux","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100022110","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100022110","name":"bioM\u00e9rieux","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100022110","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            In this study, we compared the bioNexia test (bioM\u00e9rieux, Marcy-l'\u00c9toile, France), a new immunochromatographic assay for the detection of\n            <jats:named-content content-type=\"genus-species\">Legionella pneumophila<\/jats:named-content>\n            serogroup 1 in urine, with the BinaxNOW urinary antigen test (Alere, Waltham, Massachusetts, USA). After 15 min of incubation (in accordance with the manufacturers' instructions), the sensitivities and specificities were, respectively, 76.5% and 97.2% for the bioNexia test and 87.1% and 100% for the BinaxNOW test. After a prolonged incubation time of 60 min, the sensitivities and specificities increased to, respectively, 89.4% and 97.2% for the bioNexia test and 91.8% and 100% for the BinaxNOW test. When the tests were read after 15 min, the concentration of discrepant urine samples increased the sensitivities to 94.1% for both tests. In conclusion, we found that although the bioNexia test showed lower sensitivity for the detection of\n            <jats:named-content content-type=\"genus-species\">L. pneumophila<\/jats:named-content>\n            antigen in nonconcentrated urine compared to the BinaxNOW test, a prolonged incubation time as well as the use of concentrated samples showed comparable sensitivities for both tests.\n          <\/jats:p>","DOI":"10.1128\/jcm.02448-16","type":"journal-article","created":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:34:40Z","timestamp":1490229280000},"page":"1733-1737","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of the bioNexia Legionella Test, Including Impact of Incubation Time Extension, for Detection of Legionella pneumophila Serogroup 1 Antigen in Urine"],"prefix":"10.1128","volume":"55","author":[{"given":"Paul","family":"Badoux","sequence":"first","affiliation":[{"name":"Regional Public Health Laboratory Kennemerland, Boerhaavelaan, Haarlem, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sjoerd M.","family":"Euser","sequence":"additional","affiliation":[{"name":"Regional Public Health Laboratory Kennemerland, Boerhaavelaan, Haarlem, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob P.","family":"Bruin","sequence":"additional","affiliation":[{"name":"Regional Public Health Laboratory Kennemerland, Boerhaavelaan, Haarlem, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick P. G.","family":"Mulder","sequence":"additional","affiliation":[{"name":"Regional Public Health Laboratory Kennemerland, Boerhaavelaan, Haarlem, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ed P. F.","family":"Yzerman","sequence":"additional","affiliation":[{"name":"Regional Public Health Laboratory Kennemerland, Boerhaavelaan, Haarlem, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-014-2067-1"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/586741"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.15.3.506-526.2002"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70713-3"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2006.01587.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00397-09"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00029-14"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01916-14"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03340-15"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.10.2628-2629.1996"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.1.467-468.2004"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.041996-0"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-008-0697-x"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.5402\/2013\/847283"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/jtm\/tav004"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.3.1124-1127.2002"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.02448-16","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.02448-16","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T09:00:35Z","timestamp":1646470835000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.02448-16"}},"subtitle":[],"editor":[{"given":"Andrew B.","family":"Onderdonk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["10.1128\/JCM.02448-16"],"URL":"https:\/\/doi.org\/10.1128\/jcm.02448-16","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"2016-12-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-03-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}