{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T20:13:53Z","timestamp":1769976833112,"version":"3.49.0"},"reference-count":12,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2010,7]]},"abstract":"ABSTRACT<\/jats:title>\n \n Clonorchis sinensis<\/jats:italic>\n is still a common parasite in South Korea. An enzyme-linked immunosorbent assay (ELISA) was developed to replace the usual intradermal test, and its performance in an area of endemicity was evaluated. From 2004 to 2006, 182 adults were included. The patient group consisted of 51 adults; 43 patients showed fluke eggs by microscopy, and 8 had their disease diagnosed clinically. The negative-control group included 131 adults: 98 at low risk and 33 at high risk of infestation. Both intradermal testing and ELISA were performed for all patients, and the sensitivity and specificity were evaluated. Statistical analysis for specificity looked at two groups: those at high risk and those at low risk. The sensitivity of the\n C. sinensis<\/jats:italic>\n ELISA was 80.4%, while that of the intradermal test was 56.9% (\n P<\/jats:italic>\n = 0.019). The specificities of the\n C. sinensis<\/jats:italic>\n ELISA in the low-risk and high-risk groups were 93.9% and 33.3%, respectively, while those of the intradermal test were 85.7% and 30.3%, respectively (\n P<\/jats:italic>\n = 0.0968,\n P<\/jats:italic>\n = 0.9979). The\n C. sinensis<\/jats:italic>\n ELISA may be more useful than the intradermal test; however, because of its low specificity, it may not be used independently for the diagnosis of\n C. sinensis<\/jats:italic>\n infestation or a prevalence survey in a high-risk group.\n <\/jats:p>","DOI":"10.1128\/jcm.02506-09","type":"journal-article","created":{"date-parts":[[2010,4,27]],"date-time":"2010-04-27T02:28:25Z","timestamp":1272335305000},"page":"2365-2367","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":29,"title":["Performance of an Enzyme-Linked Immunosorbent Assay for Detection of\n Clonorchis sinensis<\/i>\n Infestation in High- and Low-Risk Groups"],"prefix":"10.1128","volume":"48","author":[{"given":"Young Jin","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, School of Medicine, and Medical Research Institute, Pusan National University, Busan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Min","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, School of Medicine, and Medical Research Institute, Pusan National University, Busan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Go Eun","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, School of Medicine, and Medical Research Institute, Pusan National University, Busan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Hyun","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, School of Medicine, and Medical Research Institute, Pusan National University, Busan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyung Hoi","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, School of Medicine, and Medical Research Institute, Pusan National University, Busan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun Yup","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, School of Medicine, and Medical Research Institute, Pusan National University, Busan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chulhun L.","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, School of Medicine, and Medical Research Institute, Pusan National University, Busan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2008.46.3.133"},{"key":"e_1_3_1_3_2","first-page":"139","volume":"6","year":"2003","unstructured":"Choi, J. C., S. H. Oh, H. J. Jeong, J. H. Shin, K. H. Park, E. Y. Lee, and C. L. Chang. 2003. Evaluation of diagnostic utility of intradermal test for the diagnosis of Clonorchis sinensis infestation. Korean J. Clin. Microbiol. 6 : 139-143.","journal-title":"Korean J. Clin. Microbiol."},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2003.41.1.35"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.1988.26.1.1"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2805"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2002.40.4.191"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.86"},{"key":"e_1_3_1_9_2","first-page":"126","volume":"23","year":"2003","unstructured":"Lee, S.-H., M.-N. Kim, B.-Y. Back, J.-Y. Choi, T.-H. Kim, and Y.-S. Hwang. 2003. Analysis of parasite-specific-antibody positive patients for Clonorchis sinensis, Paragonimus westermani, Cysticercus and Sparganum using ELISA. Korean J. Lab. Med. 23 : 126-131.","journal-title":"Korean J. Lab. Med."},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00342-07"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2009.03.003"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365540601148483"},{"key":"e_1_3_1_13_2","first-page":"814","volume":"11","year":"2004","unstructured":"Zhao, Q. P., S. U. Moon, H. W. Lee, B. K. Na, S. Y. Cho, Y. Kong, M. S. Jiang, A. H. Li, and T. S. Kim. 2004. Evaluation of Clonorchis sinensis recombinant 7-kilodalton antigen for serodiagnosis of clonorchiasis. Clin. Diagn. Lab. Immunol. 11 : 814-817.","journal-title":"Clin. Diagn. Lab. Immunol."}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.02506-09","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.02506-09","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T08:39:54Z","timestamp":1646469594000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.02506-09"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.1128\/JCM.02506-09"],"URL":"https:\/\/doi.org\/10.1128\/jcm.02506-09","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7]]},"assertion":[{"value":"2009-12-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-04-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-07-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}