{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:41:51Z","timestamp":1791852111467,"version":"4.3.4"},"reference-count":26,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2014,12,20]],"date-time":"2014-12-20T00:00:00Z","timestamp":1419033600000},"content-version":"vor","delay-in-days":353,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The\n            <jats:named-content content-type=\"genus-species\">Chlamydia trachomatis<\/jats:named-content>\n            plasmid is a virulence factor. Plasmid copy number,\n            <jats:named-content content-type=\"genus-species\">C. trachomatis<\/jats:named-content>\n            load and disease severity were assessed in a treatment-naive population where trachoma is hyperendemic. By using droplet digital PCR, plasmid copy number was found to be stable (median, 5.34 [range, 1 to 18]) and there were no associations with\n            <jats:named-content content-type=\"genus-species\">C. trachomatis<\/jats:named-content>\n            load or disease severity.\n          <\/jats:p>","DOI":"10.1128\/jcm.02618-13","type":"journal-article","created":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T03:59:03Z","timestamp":1383796743000},"page":"324-327","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":33,"title":["Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection"],"prefix":"10.1128","volume":"52","author":[{"given":"Anna R.","family":"Last","sequence":"first","affiliation":[{"name":"Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chrissy h.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunice","family":"Cassama","sequence":"additional","affiliation":[{"name":"Programa Nacional de Sa\u00fade de Vis\u00e3o, Minist\u00e9rio de Sa\u00fade Publica, Bissau, Guinea Bissau"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meno","family":"Nabicassa","sequence":"additional","affiliation":[{"name":"Programa Nacional de Sa\u00fade de Vis\u00e3o, Minist\u00e9rio de Sa\u00fade Publica, Bissau, Guinea Bissau"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Molina-Gonzalez","sequence":"additional","affiliation":[{"name":"Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Burr","sequence":"additional","affiliation":[{"name":"Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom"},{"name":"Disease Control and Elimination Theme, Medical Research Council Unit The Gambia, Fajara, The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C. 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