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New, highly sensitive diagnostic methods have been developed for protozoa endemic to developed countries, including<jats:named-content content-type=\"genus-species\">Giardia lamblia<\/jats:named-content>(syn.<jats:italic>G. intestinalis\/G. duodenalis<\/jats:italic>) and<jats:named-content content-type=\"genus-species\">Cryptosporidium<\/jats:named-content>spp., using technologies that, if expanded, could effectively complement or even replace microscopic approaches. To date, the scope of such novel technologies is limited and may not include common protozoa such as<jats:named-content content-type=\"genus-species\">Dientamoeba fragilis<\/jats:named-content>,<jats:named-content content-type=\"genus-species\">Entamoeba histolytica<\/jats:named-content>, or<jats:named-content content-type=\"genus-species\">Cyclospora cayetanensis<\/jats:named-content>. This minireview describes canonical approaches for the detection of pathogenic intestinal protozoa, while highlighting recent developments and FDA-approved tools for clinical diagnosis of common intestinal protozoa.<\/jats:p>","DOI":"10.1128\/jcm.02877-13","type":"journal-article","created":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T03:59:03Z","timestamp":1383796743000},"page":"712-720","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":178,"title":["Detection of Intestinal Protozoa in the Clinical Laboratory"],"prefix":"10.1128","volume":"52","author":[{"given":"Ian H.","family":"McHardy","sequence":"first","affiliation":[{"name":"Pathology and Laboratory Medicine, UCLA, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Wu","sequence":"additional","affiliation":[{"name":"Pathology and Laboratory Medicine, UCLA, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robyn","family":"Shimizu-Cohen","sequence":"additional","affiliation":[{"name":"Pathology and Laboratory Medicine, UCLA, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc Roger","family":"Couturier","sequence":"additional","affiliation":[{"name":"Associated Regional and University Pathologists Laboratories, Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA"},{"name":"Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romney M.","family":"Humphries","sequence":"additional","affiliation":[{"name":"Pathology and Laboratory Medicine, UCLA, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.05038-11"},{"key":"e_1_3_2_3_2","unstructured":"Centers for Disease Control and Prevention. 2013. 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