{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T00:27:44Z","timestamp":1782520064544,"version":"3.54.5"},"reference-count":17,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>Fifty-five hospitals in the United States have been designated Ebola treatment centers (ETCs) by their state and local health authorities. Designated ETCs must have appropriate plans to manage a patient with confirmed Ebola virus disease (EVD) for the full duration of illness and must have these plans assessed through a CDC site visit conducted by an interdisciplinary team of subject matter experts. This study determined the clinical laboratory capabilities of these ETCs. ETCs were electronically surveyed on clinical laboratory characteristics. Survey responses were returned from 47 ETCs (85%). Forty-one (87%) of the ETCs planned to provide some laboratory support (e.g., point-of-care [POC] testing) within the room of the isolated patient. Forty-four (94%) ETCs indicated that their hospital would also provide clinical laboratory support for patient care. Twenty-two (50%) of these ETC clinical laboratories had biosafety level 3 (BSL-3) containment. Of all respondents, 34 (72%) were supported by their jurisdictional public health laboratory (PHL), all of which had available BSL-3 laboratories. Overall, 40 of 44 (91%) ETCs reported BSL-3 laboratory support via their clinical laboratory and\/or PHL. This survey provided a snapshot of the laboratory support for designated U.S. ETCs. ETCs have approached high-level isolation critical care with laboratory support in close proximity to the patient room and by distributing laboratory support among laboratory resources. Experts might review safety considerations for these laboratory testing\/diagnostic activities that are novel in the context of biocontainment care.<\/jats:p>","DOI":"10.1128\/jcm.02905-15","type":"journal-article","created":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T03:39:03Z","timestamp":1454557143000},"page":"1031-1035","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":22,"title":["U.S. Ebola Treatment Center Clinical Laboratory Support"],"prefix":"10.1128","volume":"54","author":[{"given":"Katelyn C.","family":"Jelden","sequence":"first","affiliation":[{"name":"Department of Environmental, Agricultural, and Occupational Health, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter C.","family":"Iwen","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA"},{"name":"Nebraska Public Health Laboratory, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn J.","family":"Herstein","sequence":"additional","affiliation":[{"name":"Department of Environmental, Agricultural, and Occupational Health, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul D.","family":"Biddinger","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Division of Emergency Preparedness, Massachusetts General Hospital, Boston, Massachusetts, USA"},{"name":"Department of Emergency Medicine, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen S.","family":"Kraft","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA"},{"name":"Department of Medicine, Division of Infectious Diseases, Emory University, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Saiman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Columbia University Medical Center, New York, New York, USA"},{"name":"Department of Infection Prevention and Control, New York-Presbyterian Hospital, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip W.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela L.","family":"Hewlett","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn G.","family":"Gibbs","sequence":"additional","affiliation":[{"name":"Department of Environmental, Agricultural, and Occupational Health, University of Nebraska Medical Center, Omaha, Nebraska, USA"},{"name":"Department of Environmental Health, Indiana University School of Public Health, Bloomington, Indiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Lowe","sequence":"additional","affiliation":[{"name":"Department of Environmental, Agricultural, and Occupational Health, University of Nebraska Medical Center, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.15041"},{"key":"e_1_3_2_3_2","volume-title":"New York doctor, back from Africa, is sick with Ebola, p A1","author":"Santora M","year":"2014","unstructured":"Santora M. 24 October 2014. New York doctor, back from Africa, is sick with Ebola, p A1. New York Times, New York, NY."},{"key":"e_1_3_2_4_2","volume-title":"HHS invests in enhancing domestic preparedness efforts for Ebola","author":"HHS","year":"2015","unstructured":"HHS. 2015. HHS invests in enhancing domestic preparedness efforts for Ebola. HHS, Washington, DC."},{"key":"e_1_3_2_5_2","volume-title":"hospital preparedness for patients under investigation (PUIs) or with confirmed Ebola virus disease (EVD): a framework for a tiered approach","author":"CDC","year":"2015","unstructured":"CDC. 2015. Interim guidance for U.S. hospital preparedness for patients under investigation (PUIs) or with confirmed Ebola virus disease (EVD): a framework for a tiered approach. CDC, Atlanta, GA."},{"key":"e_1_3_2_6_2","volume-title":"Guidance for collection, transport and submission of specimens for Ebola virus testing","author":"CDC","year":"2015","unstructured":"CDC. 2015. Guidance for collection, transport and submission of specimens for Ebola virus testing. CDC, Atlanta, GA."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1409838"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000935"},{"key":"e_1_3_2_9_2","volume-title":"laboratories for managing and testing routine clinical specimens when there is a concern about Ebola virus disease","author":"CDC","year":"2015","unstructured":"CDC. 2015. Guidance for U.S. laboratories for managing and testing routine clinical specimens when there is a concern about Ebola virus disease. CDC, Atlanta, GA."},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1309\/LMTULFM62W3RKMYI"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201408-1514CP"},{"key":"e_1_3_2_12_2","volume-title":"Interim guidance for preparing Ebola treatment centers","author":"CDC","year":"2014","unstructured":"CDC. 2014. 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