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Histological examination of the brains revealed variable degrees of nonsuppurative encephalitis or meningoencephalitis, characterized predominantly by perivascular lymphohistiocytic infiltrates. A PCR assay was used on brain and other available tissues to detect the presence of morbillivirus, herpesvirus, West Nile virus,\n            <jats:named-content content-type=\"genus-species\">Toxoplasma gondii<\/jats:named-content>\n            , and\n            <jats:named-content content-type=\"genus-species\">Brucella<\/jats:named-content>\n            spp. In addition, immunohistochemical (IHC) staining was performed on selected tissues to determine the presence of morbilliviral antigens. Six animals (5 striped dolphins and 1 common dolphin) showed IHC and\/or molecular evidence of morbilliviral antigens and\/or genomes, mainly in brain tissue. Conventional nested PCR detected herpesviral DNA in brain tissue samples from two striped dolphins. There was no evidence of West Nile virus,\n            <jats:named-content content-type=\"genus-species\">T. gondii<\/jats:named-content>\n            , or\n            <jats:named-content content-type=\"genus-species\">Brucella<\/jats:named-content>\n            spp. in any of the brain tissue samples examined. The information presented here increases the number of confirmed morbillivirus-positive cases within the Canarian archipelago from two previously reported cases to eight. Furthermore, a new nested-PCR method for the detection of morbillivirus is described here. Regarding herpesvirus, the phylogenetic analysis performed in the current study provides valuable information about a possible pathogenic branch of cetacean alphaherpesviruses that might be responsible for some fatal cases worldwide.\n          <\/jats:p>","DOI":"10.1128\/jcm.02906-13","type":"journal-article","created":{"date-parts":[[2014,4,24]],"date-time":"2014-04-24T03:17:39Z","timestamp":1398309459000},"page":"2390-2397","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":77,"title":["Retrospective Study of Etiologic Agents Associated with Nonsuppurative Meningoencephalitis in Stranded Cetaceans in the Canary Islands"],"prefix":"10.1128","volume":"52","author":[{"given":"Eva","family":"Sierra","sequence":"first","affiliation":[{"name":"Department of Veterinary Pathology, Institute for Animal Health, Veterinary School, Universidad de Las Palmas de Gran Canaria, Arucas, Las Palmas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Athens Veterinary Diagnostic Laboratory, University of Georgia, Athens, Georgia, USA"},{"name":"Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremiah T.","family":"Saliki","sequence":"additional","affiliation":[{"name":"Athens Veterinary Diagnostic Laboratory, University of Georgia, Athens, Georgia, USA"},{"name":"Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uriel","family":"Blas-Machado","sequence":"additional","affiliation":[{"name":"Athens Veterinary Diagnostic Laboratory, University of Georgia, Athens, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Arbelo","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Institute for Animal Health, Veterinary School, Universidad de Las Palmas de Gran Canaria, Arucas, Las Palmas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Zucca","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Institute for Animal Health, Veterinary School, Universidad de Las Palmas de Gran Canaria, Arucas, Las Palmas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Institute for Animal Health, Veterinary School, Universidad de Las Palmas de Gran Canaria, Arucas, Las Palmas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3354\/dao02558"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1993.1217"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/348021a0"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(98)80045-5"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0601.000107"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/030098589202900101"},{"key":"e_1_3_3_8_2","first-page":"524","article-title":"The striped dolphin epizootic in the Mediterranean Sea","volume":"22","author":"Aguilar A","year":"1993","unstructured":"AguilarA RagaJA. 1993. 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