{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T01:08:22Z","timestamp":1776992902073,"version":"3.51.4"},"reference-count":39,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The filamentous basidiomycete\n            <jats:named-content content-type=\"genus-species\">Ceriporia lacerata<\/jats:named-content>\n            , an agent of white rot on wood, has never been reported in human disease and its clinical significance is not yet known. We describe 4 patients with respiratory diseases where\n            <jats:named-content content-type=\"genus-species\">C. lacerata<\/jats:named-content>\n            was implicated in a wide spectrum of clinical manifestations ranging from saprobic colonization to fungal pneumonia. The isolates did not show the morphological characteristics that facilitate recognition of filamentous basidiomycetes, such as the presence of clamp connections, spicules along hyphae, or fruiting bodies. The identity of the mold was confirmed by sequencing the internal transcribed spacer 1 and 4 (ITS-1 and ITS-4) and D1\/D2 regions of the rRNA gene. All of the isolates exhibited the lowest MICs of posaconazole and isavuconazole (MIC range, 0.06 to 0.125 \u03bcg\/ml), followed by itraconazole (MIC range, 0.06 to 0.5 \u03bcg\/ml), voriconazole (MIC range, 0.125 to 0.5 \u03bcg\/ml), and amphotericin B (MIC range, 0.25 to 1 \u03bcg\/ml). The infections reported here occurred in patients with preexisting lung damage induced by tuberculosis or chronic obstructive pulmonary disease. Chronic, sometimes fatal infections by the ascomycete\n            <jats:named-content content-type=\"genus-species\">Aspergillus fumigatus<\/jats:named-content>\n            and the basidiomycete S\n            <jats:named-content content-type=\"genus-species\">chizophyllum commune<\/jats:named-content>\n            are well established in the presence of an anatomical pulmonary defect or in the background of immunodeficiency. It is postulated that\n            <jats:named-content content-type=\"genus-species\">C. lacerata<\/jats:named-content>\n            , a novel opportunist basidiomycete, may be involved in similar pathological processes.\n          <\/jats:p>","DOI":"10.1128\/jcm.02943-12","type":"journal-article","created":{"date-parts":[[2012,12,14]],"date-time":"2012-12-14T01:48:56Z","timestamp":1355449736000},"page":"585-590","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":43,"title":["Clinical Significance of Filamentous Basidiomycetes Illustrated by Isolates of the Novel Opportunist Ceriporia lacerata from the Human Respiratory Tract"],"prefix":"10.1128","volume":"51","author":[{"given":"Anuradha","family":"Chowdhary","sequence":"first","affiliation":[{"name":"Departments of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kshitij","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shallu","family":"Kathuria","sequence":"additional","affiliation":[{"name":"Departments of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"Departments of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Roy","sequence":"additional","affiliation":[{"name":"Departments of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. N.","family":"Gaur","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. S.","family":"de Hoog","sequence":"additional","affiliation":[{"name":"CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques F.","family":"Meis","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands"},{"name":"Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/13693780701449425"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01684-06"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01948-09"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01863-12"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00393569"},{"key":"e_1_3_2_7_2","first-page":"179","article-title":"Hormographiella, a new genus of hyphomycetes from clinical sources","volume":"45","author":"Guarro J","year":"1992","unstructured":"GuarroJ Gen\u00e9J de VroeyC Gu\u00e9hoE. 1992. 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