{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:55:39Z","timestamp":1789692939258,"version":"4.0.1"},"reference-count":42,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T00:00:00Z","timestamp":1613606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2021,2,18]]},"abstract":"<jats:p>With the approach of respiratory virus season in the Northern Hemisphere, clinical microbiology and public health laboratories will need rapid diagnostic assays to distinguish severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from influenza virus and respiratory syncytial virus (RSV) infections for diagnosis and surveillance. In this study, the clinical performance of the Xpert Xpress SARS-CoV-2\/Flu\/RSV test (Cepheid, Sunnyvale, CA, USA) for nasopharyngeal swab specimens was evaluated in four centers: Johns Hopkins Medical Microbiology Laboratory, Northwell Health Laboratories, NYC Public Health Laboratory, and Los Angeles County\/University of Southern California (LAC+USC) Medical Center.<\/jats:p>","DOI":"10.1128\/jcm.02955-20","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T13:51:15Z","timestamp":1607608275000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":82,"title":["Multicenter Evaluation of the Cepheid Xpert Xpress SARS-CoV-2\/Flu\/RSV Test"],"prefix":"10.1128","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0274-8966","authenticated-orcid":true,"given":"Heba H.","family":"Mostafa","sequence":"first","affiliation":[{"name":"The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen C.","family":"Carroll","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Hicken","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0767-6826","authenticated-orcid":true,"given":"Gregory J.","family":"Berry","sequence":"additional","affiliation":[{"name":"Northwell Health Laboratories, Zucker SOM at Hofstra\/Northwell, East Garden City, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryhana","family":"Manji","sequence":"additional","affiliation":[{"name":"Northwell Health Laboratories, Zucker SOM at Hofstra\/Northwell, East Garden City, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Smith","sequence":"additional","affiliation":[{"name":"Northwell Health Laboratories, Zucker SOM at Hofstra\/Northwell, East Garden City, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9464-7723","authenticated-orcid":true,"given":"Jennifer L.","family":"Rakeman","sequence":"additional","affiliation":[{"name":"NYC Public Health Laboratory, Department of Health and Mental Hygiene, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randal C.","family":"Fowler","sequence":"additional","affiliation":[{"name":"NYC Public Health Laboratory, Department of Health and Mental Hygiene, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3702-2938","authenticated-orcid":true,"given":"Mindy","family":"Leelawong","sequence":"additional","affiliation":[{"name":"NYC Public Health Laboratory, Department of Health and Mental Hygiene, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5372-8706","authenticated-orcid":true,"given":"Susan M.","family":"Butler-Wu","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of USC, Department of Pathology, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Quintero","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of USC, Department of Pathology, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minette","family":"Umali-Wilcox","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of USC, Department of Pathology, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert W.","family":"Kwiatkowski","sequence":"additional","affiliation":[{"name":"Cepheid, Sunnyvale, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H.","family":"Persing","sequence":"additional","affiliation":[{"name":"Cepheid, Sunnyvale, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Weir","sequence":"additional","affiliation":[{"name":"Cepheid, Sunnyvale, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3934-089X","authenticated-orcid":true,"given":"Michael J.","family":"Loeffelholz","sequence":"additional","affiliation":[{"name":"Cepheid, Sunnyvale, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.14661"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.6266"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31052-7"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2020.06.011"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.05.041"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2020.e00775"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2606.200299"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00926-20"},{"key":"e_1_3_2_10_2","volume-title":"Guide for considering influenza testing when influenza viruses are circulating in the community","author":"CDC","year":"2020","unstructured":"CDC. 2020. Guide for considering influenza testing when influenza viruses are circulating in the community. CDC, Atlanta, GA."},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy866"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00743-20"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00760-20"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2020.104384"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2020.104416"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00821-20"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00783-20"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00890-20"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2020.104383"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00798-20"},{"key":"e_1_3_2_21_2","doi-asserted-by":"crossref","unstructured":"Basu A Zinger T Inglima K Woo K Atie O Yurasits L See B Aguero-Rosenfeld ME. 2020. Performance of the rapid nucleic acid amplification by Abbott ID NOW COVID-19 in nasopharyngeal swabs transported in viral media and dry nasal swabs in a New York City academic institution. bioRxiv https:\/\/www.biorxiv.org\/content\/10.1101\/2020.05.11.089896v1.","DOI":"10.1101\/2020.05.11.089896"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00938-20"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2020.104428"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01072-20"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00772-20"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25988"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00599-20"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00753-20"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2020.104578"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2020.104583"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00512-20"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30196-1"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2196-x"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020200642"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2016359"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqaa181"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2020.115200"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2020.09.035"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-019-03752-3"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01611-19"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idh.2019.11.001"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2019.08.022"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2019.01.003"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.02955-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.02955-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T10:54:09Z","timestamp":1646477649000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.02955-20"}},"subtitle":[],"editor":[{"given":"Alexander J.","family":"McAdam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,2,18]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,2,18]]}},"alternative-id":["10.1128\/JCM.02955-20"],"URL":"https:\/\/doi.org\/10.1128\/jcm.02955-20","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,18]]},"assertion":[{"value":"2020-11-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e02955-20"}}