{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:01:51Z","timestamp":1791248511516,"version":"4.1.0"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The use of molecular identification techniques has revealed an increasing number of new species within\n            <jats:named-content content-type=\"genus-species\">Aspergillus<\/jats:named-content>\n            section\n            <jats:named-content content-type=\"genus-species\">Terrei<\/jats:named-content>\n            . We phenotyped a set of 26 clinical isolates that showed genetic differences from\n            <jats:named-content content-type=\"genus-species\">Aspergillus terreus<\/jats:named-content>\n            <jats:named-content content-type=\"genus-species\">sensu stricto<\/jats:named-content>\n            by analyzing sequences from PCR-amplified \u03b2-tubulin and calmodulin genes and the internal transcribed spacer region. Since the isolates were phylogenetically and morphologically different from all of the members of\n            <jats:named-content content-type=\"genus-species\">Aspergillus<\/jats:named-content>\n            section\n            <jats:named-content content-type=\"genus-species\">Terrei<\/jats:named-content>\n            , they are described here as a new species,\n            <jats:named-content content-type=\"genus-species\">Aspergillus<\/jats:named-content>\n            <jats:named-content content-type=\"genus-species\">citrinoterreus<\/jats:named-content>\n            , so named because it produces a diffusible yellowish pigment in agar.\n            <jats:named-content content-type=\"genus-species\">A. citrinoterreus<\/jats:named-content>\n            isolates were significantly more susceptible to itraconazole, voriconazole, and posaconazole than\n            <jats:named-content content-type=\"genus-species\">A. terreus<\/jats:named-content>\n            <jats:named-content content-type=\"genus-species\">sensu stricto<\/jats:named-content>\n            isolates were; in contrast, the amphotericin B MICs for both species were high.\n            <jats:named-content content-type=\"genus-species\">A. citrinoterreus<\/jats:named-content>\n            was found in clinical samples from patients with proven or probable invasive aspergillosis and colonized patients, none of whom had hematological malignancies as predisposing conditions. However, they did have other underlying conditions such as chronic obstructive pulmonary disease, cirrhosis, and cancer or had received a solid organ transplants and presented not only with invasive pulmonary aspergillosis but also with mediastinitis.\n            <jats:named-content content-type=\"genus-species\">A. citrinoterreus<\/jats:named-content>\n            isolates were detected for the first time in 2002. In all cases of invasive aspergillosis,\n            <jats:named-content content-type=\"genus-species\">A. citrinoterreus<\/jats:named-content>\n            was found to be a copathogen, mostly with\n            <jats:named-content content-type=\"genus-species\">A. fumigatus<\/jats:named-content>\n            .\n          <\/jats:p>","DOI":"10.1128\/jcm.03088-14","type":"journal-article","created":{"date-parts":[[2014,12,11]],"date-time":"2014-12-11T02:35:28Z","timestamp":1418265328000},"page":"611-617","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":36,"title":["Aspergilluscitrinoterreus, a New Species of Section Terrei Isolated from Samples of Patients with Nonhematological Predisposing Conditions"],"prefix":"10.1128","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7901-8355","authenticated-orcid":false,"given":"Jes\u00fas","family":"Guinea","sequence":"first","affiliation":[{"name":"Clinical 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