{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:24:04Z","timestamp":1787793844799,"version":"build-2784847793"},"reference-count":39,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Eosinophilic fasciitis (EF) with generalized sclerodermiform skin lesions developed over a 19-month period in a previously healthy 23-year-old man. Although we confirmed EF by skin histology and laboratory tests, the recurrent fevers and the clinical observation of sclerotic prepuce with urethritis indicated further bacteriological analysis by conventional microbiological and DNA-based tests. Urethra cultures were positive for an arginine-hydrolyzing mycoplasma and\n            <jats:named-content content-type=\"genus-species\">Ureaplasma urealyticum<\/jats:named-content>\n            . The patient also had serum IgM antibodies to\n            <jats:named-content content-type=\"genus-species\">Mycoplasma pneumoniae<\/jats:named-content>\n            using enzyme-linked immunosorbent assay (ELISA)-based qualitative detection.\n            <jats:named-content content-type=\"genus-species\">Mycoplasma arginini<\/jats:named-content>\n            was isolated from two independent venous blood serum samples and was identified by conventional microbiological tests and sequencing of the 16S rRNA and\n            <jats:italic>rpoB<\/jats:italic>\n            genes (GenBank sequence accession numbers\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"gen\" xlink:href=\"HM179555\">HM179555<\/jats:ext-link>\n            and\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"gen\" xlink:href=\"HM179556\">HM179556<\/jats:ext-link>\n            , respectively).\n            <jats:named-content content-type=\"genus-species\">M. arginini<\/jats:named-content>\n            genomic DNA also was detected by species-specific PCR in the skin lesion biopsy sample. Treatment with corticosteroids and long-term courses of selected antibiotics led to remission of skin symptoms and normalization of laboratory values. This report provides the first evidence of EF associated with mycoplasma infection and the second report of human infection with\n            <jats:named-content content-type=\"genus-species\">M. arginini<\/jats:named-content>\n            and therefore suggests that this mycoplasma infection might have contributed to the pathogenesis of the disease.\n          <\/jats:p>","DOI":"10.1128\/jcm.05568-11","type":"journal-article","created":{"date-parts":[[2011,12,22]],"date-time":"2011-12-22T02:24:53Z","timestamp":1324520693000},"page":"1113-1117","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":34,"title":["Eosinophilic Fasciitis Associated with Mycoplasma arginini Infection"],"prefix":"10.1128","volume":"50","author":[{"given":"P\u00e1lma","family":"Sill\u00f3","sequence":"first","affiliation":[{"name":"Semmelweis University Hungary, Department of Dermatology, Venereology and Dermatooncology, Budapest, M\u00e1ria utca 41, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00f3ra","family":"Pint\u00e9r","sequence":"additional","affiliation":[{"name":"Semmelweis University Hungary, Department of Dermatology, Venereology and Dermatooncology, Budapest, M\u00e1ria utca 41, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"Ostorh\u00e1zi","sequence":"additional","affiliation":[{"name":"Semmelweis University Hungary, Department of Dermatology, Venereology and Dermatooncology, Budapest, M\u00e1ria utca 41, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercedes","family":"Maz\u00e1n","sequence":"additional","affiliation":[{"name":"Hungarian Academy of Sciences, Molecular Medicine Research Group, Budapest, M\u00e1ria utca 41, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Wikonk\u00e1l","sequence":"additional","affiliation":[{"name":"Semmelweis University Hungary, Department of Dermatology, Venereology and Dermatooncology, Budapest, M\u00e1ria utca 41, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katinka","family":"P\u00f3nyai","sequence":"additional","affiliation":[{"name":"Semmelweis University Hungary, Department of Dermatology, Venereology and Dermatooncology, Budapest, M\u00e1ria utca 41, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitriy V.","family":"Volokhov","sequence":"additional","affiliation":[{"name":"Division of Viral Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Rockville, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir E.","family":"Chizhikov","sequence":"additional","affiliation":[{"name":"Division of Viral Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Rockville, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Szathmary","sequence":"additional","affiliation":[{"name":"GalenBio, Inc., Carlsbad, California, USA"},{"name":"RT-Europe Research Center 9200, Mosonmagyarovar, Var 2, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laszlo","family":"Stipkovits","sequence":"additional","affiliation":[{"name":"RT-Europe Research Center 9200, Mosonmagyarovar, Var 2, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarolta","family":"K\u00e1rp\u00e1ti","sequence":"additional","affiliation":[{"name":"Semmelweis University Hungary, Department of Dermatology, Venereology and Dermatooncology, Budapest, M\u00e1ria utca 41, Hungary"},{"name":"Hungarian Academy of Sciences, Molecular Medicine Research Group, Budapest, M\u00e1ria utca 41, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000093847"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.58.3.215"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000018271"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/514980"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-129-33351"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.5.2277-2285.2005"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.27.11.2492-2496.1989"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1991.01680070059006"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002770050449"},{"key":"e_1_3_2_11_2","first-page":"589","article-title":"Analysis of L-tryptophan for the etiology of eosinophilia-myalgia syndrome","volume":"39","author":"CDC","year":"1990","unstructured":"CDC. 1990. 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