{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T12:07:06Z","timestamp":1776773226960,"version":"3.51.2"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[1990,7,1]],"date-time":"1990-07-01T00:00:00Z","timestamp":646790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[1990,7]]},"abstract":"<jats:p>The Directigen 1,2,3 Group A Strep Test (DGAST; BBL Microbiology Systems, Cockeysville, Md.) was compared with conventional culture methods for the detection of group A streptococci. Among 327 children, the DGAST has a sensitivity of 75.0%, a specificity of 99.1%, and positive and negative predictive values of 97.5 and 89.3%, respectively, as compared with 48-h culture results. The lower sensitivity (60.0%) in 322 adults was related to the low incidence of group A streptococcal pharyngitis in that population (7.8%). The positive and negative predictive values for adults were 93.8 and 96.7%, respectively. Only 3 of 327 (0.9%) pediatric and 2 of 322 (0.6%) adult specimens yielded uninterpretable results in the DGAST.<\/jats:p>","DOI":"10.1128\/jcm.28.7.1661-1663.1990","type":"journal-article","created":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T03:30:03Z","timestamp":1578195003000},"page":"1661-1663","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of the Directigen 1,2,3 Group A Strep Test for diagnosis of streptococcal pharyngitis"],"prefix":"10.1128","volume":"28","author":[{"given":"N P","family":"Moyer","sequence":"first","affiliation":[{"name":"Hygienic Laboratory, University of Iowa, Iowa City 52242."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P J","family":"Quinn","sequence":"additional","affiliation":[{"name":"Hygienic Laboratory, University of Iowa, Iowa City 52242."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C A","family":"Showalter","sequence":"additional","affiliation":[{"name":"Hygienic Laboratory, University of Iowa, Iowa City 52242."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jcm.28.7.1661-1663.1990","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jcm.28.7.1661-1663.1990","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T22:52:26Z","timestamp":1646434346000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jcm.28.7.1661-1663.1990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,7]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1990,7]]}},"alternative-id":["10.1128\/jcm.28.7.1661-1663.1990"],"URL":"https:\/\/doi.org\/10.1128\/jcm.28.7.1661-1663.1990","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,7]]},"assertion":[{"value":"1990-07-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}