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Combined PCR assay of cerebrospinal fluid and serum (systemic specimens) was more sensitive than assaying either specimen alone in children but not in adults. Compared with PCR in systemic specimens, detection of enterovirus RNA in throat swabs showed a sensitivity of 62.5% and a specificity of 75.6%.<\/jats:p>","DOI":"10.1128\/jcm.36.2.589-591.1998","type":"journal-article","created":{"date-parts":[[2019,12,31]],"date-time":"2019-12-31T17:27:12Z","timestamp":1577813232000},"page":"589-591","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":38,"title":["Comparison of Use of Cerebrospinal Fluid, Serum, and Throat Swab Specimens in Diagnosis of Enteroviral Acute Neurological Infection by a Rapid RNA Detection PCR Assay"],"prefix":"10.1128","volume":"36","author":[{"given":"Laurent","family":"Andre\u0301oletti","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Laboratoire de Virologie,1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Blassel-Damman","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Laboratoire de Virologie,1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anny","family":"Dewilde","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Laboratoire de Virologie,1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis","family":"Valle\u0301e","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->Service des Maladies Infectieuses Neurologiques Infantiles,2 and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Cremer","sequence":"additional","affiliation":[{"name":"<!--label omitted: 3-->Service de Re\u0301animation Pe\u0301diatrique,3 Centre Hospitalier Universitaire de Lille, 59037 Lille cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didier","family":"Hober","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Laboratoire de Virologie,1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Wattre\u0301","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Laboratoire de Virologie,1"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70466-3"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-0934(96)02080-0"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/168.4.888"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.26.12.2576-2580.1988"},{"key":"e_1_3_2_6_2","first-page":"397","article-title":"Viremia in hospitalized children with enterovirus infections","volume":"104","author":"Dagan R.","year":"1984","unstructured":"Dagan R. 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