{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T22:36:46Z","timestamp":1793659006374,"version":"4.5.1"},"reference-count":11,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n            has emerged as the leading liver abscess pathogen in Taiwan, with the percentage rising from 30% in the 1980s to over 80% in the 1990s. Most of the patients with\n            <jats:italic>K. pneumoniae<\/jats:italic>\n            liver abscess are diabetic and without biliary tract disease. Some patients develop serious extrahepatic complications such as endophthalmitis, meningitis, lung abscess, and necrotizing fasciitis. Pulsed-field gel electrophoresis (PFGE) was used for cluster analysis of 96 isolates from patients with liver abscess and 60 isolates from patients with other diseases. A total of 136 PFGE types were identified. Among the 96 liver abscess-associated isolates, 60 (62.5%) were classified in major cluster A. Cluster A included 41 PFGE types (types 1 to 41) which had a genetic similarity of at least 72.4% \u00b1 9.4%. The PFGE patterns of cluster A strains are so similar that they could have originated from the same ancestor. This study demonstrates that cluster A plays an important role in the high incidence of\n            <jats:italic>K. pneumoniae<\/jats:italic>\n            liver abscess in Taiwan.\n          <\/jats:p>","DOI":"10.1128\/jcm.38.1.412-414.2000","type":"journal-article","created":{"date-parts":[[2021,5,29]],"date-time":"2021-05-29T21:44:29Z","timestamp":1622324669000},"page":"412-414","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":70,"title":["Identification of a Major Cluster of\n            <i>Klebsiella pneumoniae<\/i>\n            Isolates from Patients with Liver Abscess in Taiwan"],"prefix":"10.1128","volume":"38","author":[{"given":"Yeu-Jun","family":"Lau","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Section of Infectious Diseases, Taichung Veterans General Hospital and School of Medicine, National Yang-Ming University,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bor-Shen","family":"Hu","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Section of Infectious Diseases, Taichung Veterans General Hospital and School of Medicine, National Yang-Ming University,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-Ling","family":"Wu","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Section of Infectious Diseases, Taichung Veterans General Hospital and School of Medicine, National Yang-Ming University,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Hui","family":"Lin","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Section of Infectious Diseases, Taichung Veterans General Hospital and School of Medicine, National Yang-Ming University,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hwan-You","family":"Chang","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->Microbiology and Biotechnology Laboratory, National Tsing Hua University,2 Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Yuan","family":"Shi","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Section of Infectious Diseases, Taichung Veterans General Hospital and School of Medicine, National Yang-Ming University,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1991.00400080059010"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-144-11-3049"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)44784-5"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1986.00360220057011"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.6.3140"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199603000-00006"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.36.12.3514-3519.1998"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.11.2784-2790.1996"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.33.9.2233-2239.1995"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1086\/516369"},{"key":"e_1_3_2_12_2","first-page":"1911","article-title":"Pyogenic liver abscess in Taiwan: emphasis on gas-forming liver abscess in diabetics","volume":"88","author":"Yang C.-C.","year":"1993","unstructured":"Yang C.-C. Chen C.-Y. Lin X.-Z. Chang T.-T. Shin J.-S. Lin C.-Y. Pyogenic liver abscess in Taiwan: emphasis on gas-forming liver abscess in diabetics.Am. J. Gastroenterol.88199319111915","journal-title":"Am. J. Gastroenterol."}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.38.1.412-414.2000","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.38.1.412-414.2000","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T00:33:28Z","timestamp":1646440408000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.38.1.412-414.2000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1128\/JCM.38.1.412-414.2000"],"URL":"https:\/\/doi.org\/10.1128\/jcm.38.1.412-414.2000","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1]]},"assertion":[{"value":"1999-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-10-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2000-01-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}