{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:10:10Z","timestamp":1790784610288,"version":"4.1.0"},"reference-count":16,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2000,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>The Oxoid combination disk method for detecting extended-spectrum \u03b2-lactamases (ESBLs) depends on comparing the inhibition zones of cefpodoxime (10-\u03bcg) and cefpodoxime-plus-clavulanate (10- plus 1-\u03bcg) disks. The presence of clavulanate enlarged the zones for all of 180 ESBL-producing klebsiellae by \u22655 mm, whereas zones for cefpodoxime-susceptible isolates and cefpodoxime-resistant isolates with AmpC and K1 \u03b2-lactamases were enlarged by \u22641 mm. Good discrimination was achieved with either the NCCLS or the British disk method.<\/jats:p>","DOI":"10.1128\/jcm.38.11.4228-4232.2000","type":"journal-article","created":{"date-parts":[[2019,12,31]],"date-time":"2019-12-31T17:50:57Z","timestamp":1577814657000},"page":"4228-4232","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":76,"title":["Detection of Extended-Spectrum \u03b2-Lactamases in Klebsiellae with the Oxoid Combination Disk Method"],"prefix":"10.1128","volume":"38","author":[{"given":"Michael W.","family":"Carter","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Antibiotic Resistance Monitoring and Reference Laboratory, Central Public Health Laboratory, London NW9 5HT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen J.","family":"Oakton","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Antibiotic Resistance Monitoring and Reference Laboratory, Central Public Health Laboratory, London NW9 5HT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Warner","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Antibiotic Resistance Monitoring and Reference Laboratory, Central Public Health Laboratory, London NW9 5HT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Livermore","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Antibiotic Resistance Monitoring and Reference Laboratory, Central Public Health Laboratory, London NW9 5HT, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/45.2.183"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.5.1168"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)90891-9"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.6.1211"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.8.1880-1884.1996"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/40.4.533"},{"key":"e_1_3_2_8_2","first-page":"661","article-title":"Antimicrobial susceptibility testing for Klebsiella pneumoniae isolates resistant to extended-spectrum beta-lactam antibiotics","volume":"97","author":"Jan I. S.","year":"1998","unstructured":"Jan I. S. Hsueh P. R. Teng L. J. Ho S. W. Luh K. T. Antimicrobial susceptibility testing for Klebsiella pneumoniae isolates resistant to extended-spectrum beta-lactam antibiotics.J. Formos. Med. Assoc.971998661666","journal-title":"J. Formos. Med. Assoc."},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/10.4.867"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/38.3.409"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/24.Supplement_1.S19"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/45.6.881"},{"key":"e_1_3_2_13_2","unstructured":"National Committee for Clinical Laboratory Standards\nPerformance standards for antimicrobial disk susceptibility tests 7th ed. 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