{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T10:45:55Z","timestamp":1774781155762,"version":"3.50.1"},"reference-count":24,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2000,4,1]],"date-time":"2000-04-01T00:00:00Z","timestamp":954547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2000,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The intraspecies diversity of an opportunistic yeast pathogen,\n            <jats:italic>Cryptococcus laurentii<\/jats:italic>\n            , was revealed by analysis of the sequences of the internal transcribed spacer regions and the 28S rRNA gene. Ten strains of\n            <jats:italic>C. laurentii<\/jats:italic>\n            were grouped into two major phylogenetic groups and were further divided into at least seven species. Four of the strains isolated from patients did not represent a single species but showed heterogeneity. These results suggest that\n            <jats:italic>C. laurentii<\/jats:italic>\n            is a genetically heterogeneous species, and this must be taken into consideration when identifying\n            <jats:italic>C. laurentii<\/jats:italic>\n            clinical isolates.\n          <\/jats:p>","DOI":"10.1128\/jcm.38.4.1468-1471.2000","type":"journal-article","created":{"date-parts":[[2019,12,31]],"date-time":"2019-12-31T12:55:02Z","timestamp":1577796902000},"page":"1468-1471","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":54,"title":["Intraspecies Diversity of\n            <i>Cryptococcus laurentii<\/i>\n            as Revealed by Sequences of Internal Transcribed Spacer Regions and 28S rRNA Gene and Taxonomic Position of\n            <i>C. laurentii<\/i>\n            Clinical Isolates"],"prefix":"10.1128","volume":"38","author":[{"given":"Takashi","family":"Sugita","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Department of Microbiology, Meiji Pharmaceutical University, Kiyose, Tokyo,1and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Takashima","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2--> Japan Collection of Microorganisms, RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama,2 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reiko","family":"Ikeda","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Microbiology, Meiji Pharmaceutical University, Kiyose, Tokyo,1and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Nakase","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2--> Japan Collection of Microorganisms, RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama,2 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takako","family":"Shinoda","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Microbiology, Meiji Pharmaceutical University, Kiyose, Tokyo,1and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.1985.tb00420.x"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00872392"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1994.tb00277.x"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00713938"},{"key":"e_1_3_1_6_2","first-page":"129","article-title":"Trichosporon infections: clinical manifestations and treatment","volume":"3","author":"Herbrecht R.","year":"1993","unstructured":"Herbrecht R. 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