{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T04:35:36Z","timestamp":1718771736930},"reference-count":30,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Gastric biopsy specimens from 156 adult patients from southern Estonia suffering from chronic gastritis, peptic ulcer disease, and perforated peptic ulcer were analyzed by PCR. The\n            <jats:italic>cagA<\/jats:italic>\n            gene was evenly distributed throughout 87% of the specimens from the patients with the different gastric diseases. The presence of the\n            <jats:italic>cagA<\/jats:italic>\n            gene correlated with that of\n            <jats:italic>vacA<\/jats:italic>\n            signal sequence type s1a (99%). However, no clear differences were found in the distribution of\n            <jats:italic>cagA<\/jats:italic>\n            and\n            <jats:italic>vacA<\/jats:italic>\n            genotypes among patients in Estonia with severe perforated peptic ulcer, uncomplicated peptic ulcer, or chronic gastritis.\n          <\/jats:p>","DOI":"10.1128\/jcm.40.1.298-300.2002","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:03:40Z","timestamp":1027764220000},"page":"298-300","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":26,"title":["Association of\n            <i>cagA<\/i>\n            and\n            <i>vacA<\/i>\n            Genotypes of\n            <i>Helicobacter pylori<\/i>\n            with Gastric Diseases in Estonia"],"prefix":"10.1128","volume":"40","author":[{"given":"Helena","family":"Andreson","sequence":"first","affiliation":[{"name":"Department of Microbiology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krista","family":"Lo\u0303ivukene","sequence":"additional","affiliation":[{"name":"Department of Microbiology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toomas","family":"Sillakivi","sequence":"additional","affiliation":[{"name":"Department of Surgery"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidi-Ingrid","family":"Maaroos","sequence":"additional","affiliation":[{"name":"Department of Polyclinic and Family Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mart","family":"Ustav","sequence":"additional","affiliation":[{"name":"Institute of Molecular and Cell Biology, University of Tartu, Tartu 50411, Estonia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ants","family":"Peetsalu","sequence":"additional","affiliation":[{"name":"Department of Surgery"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marika","family":"Mikelsaar","sequence":"additional","affiliation":[{"name":"Department of Microbiology"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.30.17771"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(97)70223-3"},{"key":"e_1_3_2_4_2","first-page":"21","volume":"61","year":"1995","unstructured":"Cover, T. 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