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For this report, we carried out retrospective seroepidemiologic studies on serum samples collected from residents of Liuchiu Hsiang, Pingtung County, an isolated island in southern Taiwan during 1997-1998. The results demonstrated that good correlation existed between dengue virus NS1 serotype-specific immunoglobulin G (IgG) ELISA and dengue virus plaque reduction neutralization test (PRNT). Our data suggested that NS1 serotype-specific IgG ELISA could replace PRNT for seroepidemiologic studies to differentiate Japanese encephalitis and dengue virus infections and for dengue virus serotyping.<\/jats:p>","DOI":"10.1128\/jcm.40.5.1840-1844.2002","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:09:29Z","timestamp":1027764569000},"page":"1840-1844","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":45,"title":["Potential Application of Nonstructural Protein NS1 Serotype-Specific Immunoglobulin G Enzyme-Linked Immunosorbent Assay in the Seroepidemiologic Study of Dengue Virus Infection: Correlation of Results with Those of the Plaque Reduction Neutralization Test"],"prefix":"10.1128","volume":"40","author":[{"given":"Pei-Yun","family":"Shu","sequence":"first","affiliation":[{"name":"Division of Research and Diagnosis, Center for Disease Control, Department of Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Kuang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Medical Center, Tzu Chi University, Hualien, Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Fen","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Research and Diagnosis, Center for Disease Control, Department of Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Yun","family":"Yueh","sequence":"additional","affiliation":[{"name":"Division of Research and Diagnosis, Center for Disease Control, Department of Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Chow","sequence":"additional","affiliation":[{"name":"Division of Research and Diagnosis, Center for Disease Control, Department of Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Jung","family":"Chien","sequence":"additional","affiliation":[{"name":"Division of Research and Diagnosis, Center for Disease Control, Department of Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan","family":"Chin","sequence":"additional","affiliation":[{"name":"Co-Wealth Medical Science and Biotechnology, Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Hua","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Medical Center, Tzu Chi University, Hualien, Taiwan, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting-Hsiang","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Research and Diagnosis, Center for Disease Control, Department of Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyh-Hsiung","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Research and Diagnosis, Center for Disease Control, Department of Health"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-70-1-37"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1996.0109"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0161-5890(78)90070-6"},{"key":"e_1_3_2_5_2","first-page":"20","volume":"20","year":"1996","unstructured":"Gubler, D. 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