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HuCVs were detected in 44 of 310 stool specimens (14.19%) negative for other enteric pathogens obtained from children with acute gastroenteritis. Norwalk-like viruses (NLVs) were the most common cause of the gastroenteritis outbreaks investigated here. They were detected in 14 out of 25 (56%) outbreaks with an identified pathogen. Genotypes producing both sporadic cases and outbreaks were diverse, with a predominance of GGII strains related to genotypes Melksham and Lordsdale. Five strains clustered with a \u201cnew variant\u201d designated GGIIb, which was detected circulating throughout quite a few European countries in the years 2000 and 2001. The emergence mechanism of these strains might be the occurrence of intertypic recombinations between different viruses. The nucleotide sequence of part of the capsid gene (ORF2) from three of these strains demonstrated their relationship with Mexico virus.<\/jats:p>","DOI":"10.1128\/jcm.40.8.2854-2859.2002","type":"journal-article","created":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T19:36:19Z","timestamp":1033500979000},"page":"2854-2859","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":153,"title":["Molecular Epidemiology of Caliciviruses Causing Outbreaks and Sporadic Cases of Acute Gastroenteritis in Spain"],"prefix":"10.1128","volume":"40","author":[{"given":"J.","family":"Buesa","sequence":"first","affiliation":[{"name":"Department of Microbiology, School of Medicine, Hospital Cli\u0301nico Universitario, University of Valencia, 46010 Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Collado","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Hospital Cli\u0301nico Universitario, University of Valencia, 46010 Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Lo\u0301pez-Andu\u0301jar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Hospital Cli\u0301nico Universitario, University of Valencia, 46010 Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Abu-Mallouh","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Hospital Cli\u0301nico Universitario, University of Valencia, 46010 Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Rodri\u0301guez Di\u0301az","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Hospital Cli\u0301nico Universitario, University of Valencia, 46010 Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Garci\u0301a Di\u0301az","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Hospital Cli\u0301nico Universitario, University of Valencia, 46010 Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Prat","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology, Hospital of Sagunto, 46500 Valencia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Guix","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Biology, University of Barcelona, 08028 Barcelona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Llovet","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Hospital Santa Creu i Sant Pau, Universitat Auto\u0301noma de Barcelona, 08025 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Prats","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Hospital Santa Creu i Sant Pau, Universitat Auto\u0301noma de Barcelona, 08025 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Bosch","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Biology, University of Barcelona, 08028 Barcelona"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.33.1.64-71.1995"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/315589"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.1.15-37.2001"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.9.3055-3058.1999"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.28.3.495-503.1990"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007618215377"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-76-9-2349"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1006\/mcpr.2000.0323"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1086\/314525"},{"key":"e_1_3_2_11_2","unstructured":"Gilligran P. 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