{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T07:30:36Z","timestamp":1764401436016},"reference-count":22,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2002,8,1]],"date-time":"2002-08-01T00:00:00Z","timestamp":1028160000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2002,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We investigated the phenotypic and genetic diversity (by ribotyping) of\n            <jats:italic>Streptococcus pneumoniae<\/jats:italic>\n            isolates recovered from French children, by blood culture from meningitis-free patients (\n            <jats:italic>n<\/jats:italic>\n            = 244) and by cerebrospinal fluid culture from patients with meningitis (\n            <jats:italic>n<\/jats:italic>\n            = 154). Isolates belonging to serotypes associated with carriage and penicillin-resistant isolates were significantly more frequent in children under 2 years of age than in older children. The seven-valent pneumococcal conjugate vaccine covered 68% of strains associated with bacteremia and 61% of strains associated with meningitis in children under 2 years. Although some serotypes were recovered more frequently from children with bacteremia than from those with meningitis, no difference in the genetic backgrounds of the two groups of strains was found.\n          <\/jats:p>","DOI":"10.1128\/jcm.40.8.2994-2998.2002","type":"journal-article","created":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T19:36:19Z","timestamp":1033500979000},"page":"2994-2998","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":28,"title":["Phenotypic and Genetic Diversity of Invasive Pneumococcal Isolates Recovered from French Children"],"prefix":"10.1128","volume":"40","author":[{"given":"Catherine","family":"Doit","sequence":"first","affiliation":[{"name":"Service de Microbiologie, Ho\u0302pital Robert Debre\u0301, Paris"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chawki","family":"Loukil","sequence":"additional","affiliation":[{"name":"Service de Microbiologie, Ho\u0302pital Robert Debre\u0301, Paris"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Geslin","sequence":"additional","affiliation":[{"name":"Centre National de Re\u0301fe\u0301rence des Pneumocoques, Centre Hospitalier Intercommunal, Cre\u0301teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edouard","family":"Bingen","sequence":"additional","affiliation":[{"name":"Service de Microbiologie, Ho\u0302pital Robert Debre\u0301, Paris"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1993.03500020055031"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.2.e23"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.106.2.362"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/165.1.147"},{"key":"e_1_3_1_6_2","unstructured":"de Benoist A. 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R\u00e9seau National de Sant\u00e9 Publique Saint Maurice France."},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.38.11.2655"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/315502"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200102083440602"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1086\/313609"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04222-7"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2000.tb00775.x"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.9.5217-5222.2001"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.1995.1.5"},{"key":"e_1_3_1_15_2","unstructured":"Lebart L. A. Morineau and K. M. Warwick. 1984. Multivariate descriptive analysis: correspondence analysis and related techniques for large matrices. 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National Committee for Clinical Laboratory Standards Villanova Pa."},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.13.1729"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1086\/322794"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02779-3"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02294151"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1086\/322984"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.40.8.2994-2998.2002","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.40.8.2994-2998.2002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T01:55:34Z","timestamp":1646445334000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.40.8.2994-2998.2002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,8]]},"references-count":22,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2002,8]]}},"alternative-id":["10.1128\/JCM.40.8.2994-2998.2002"],"URL":"https:\/\/doi.org\/10.1128\/jcm.40.8.2994-2998.2002","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,8]]},"assertion":[{"value":"2002-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2002-05-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2002-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}