{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T07:10:58Z","timestamp":1773299458126,"version":"3.50.1"},"reference-count":23,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A 45-year-old man from Nepal with a 13-year history of polycystic kidney disease was diagnosed as suffering from chronic renal failure with end-stage renal disease. After receiving empirical antituberculosis treatment, he was treated with broad-spectrum antibiotics. A left nephrectomy was performed, and after 4 months, he received a kidney transplant. The left kidney was grossly enlarged, with multiple cystic spaces filled with blackish material. Histologic examination of the excised left kidney tissue stained with hematoxylin and eosin and Gomori's methenamine silver stains showed numerous hyaline, septate, fungal hyphae of various lengths, many broken into rectangular arthroconidia in the cystic spaces. Culture of the kidney tissue yielded white, glabrous, yeast-like colonies. Based on its micromorphology, growth at 42\u00b0C, and ribosomal DNA (rDNA) sequence analysis, and also sequence analysis of the internal-transcribed-spacer and D1\/D2 rDNA regions, the yeast was identified as\n            <jats:italic>Trichosporon loubieri.<\/jats:italic>\n            Postsurgically, the patient was treated with amphotericin B and oral itraconazole, followed by maintenance therapy with fluconazole. He remained afebrile and asymptomatic. At the final follow-up, all parameters were found normal and the patient was doing well, with normal renal function reports. This paper presents the first known case of human infection caused by\n            <jats:italic>T. loubieri.<\/jats:italic>\n          <\/jats:p>","DOI":"10.1128\/jcm.41.1.479-482.2003","type":"journal-article","created":{"date-parts":[[2003,1,7]],"date-time":"2003-01-07T18:03:11Z","timestamp":1041962591000},"page":"479-482","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":43,"title":["<i>Trichosporon loubieri<\/i>\n            Infection in a Patient with Adult Polycystic Kidney Disease"],"prefix":"10.1128","volume":"41","author":[{"given":"Arvind A.","family":"Padhye","sequence":"first","affiliation":[{"name":"Mycotic Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Verghese","sequence":"additional","affiliation":[{"name":"Institute of Cardio-Vascular Diseases, Madras Medical Mission"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Ravichandran","sequence":"additional","affiliation":[{"name":"Department of Kidney Diseases, Institute of Orthopaedics and Traumatology, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Balamurugan","sequence":"additional","affiliation":[{"name":"Department of Kidney Diseases, Institute of Orthopaedics and Traumatology, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie","family":"Hall","sequence":"additional","affiliation":[{"name":"Division of Clinical Microbiology, Mayo Clinic, Mayo Foundation, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Padmaja","sequence":"additional","affiliation":[{"name":"Institute of Cardio-Vascular Diseases, Madras Medical Mission"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Institute of Cardio-Vascular Diseases, Madras Medical Mission"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/15.5.781"},{"key":"e_1_3_2_3_2","unstructured":"Barnett J. 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