{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T22:30:17Z","timestamp":1789425017265,"version":"build-2803163510"},"reference-count":24,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2003,4,1]],"date-time":"2003-04-01T00:00:00Z","timestamp":1049155200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2003,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            <jats:italic>Nocardia veterana<\/jats:italic>\n            is a newly described species named after the veteran's hospital where it was first isolated. This initial type strain was not thought to be clinically significant. We describe three cases of pulmonary disease attributable to\n            <jats:italic>N<\/jats:italic>\n            .\n            <jats:italic>veterana<\/jats:italic>\n            : two cases in patients presenting with multiple pulmonary nodules in a setting of immunocompromise and one case of exacerbation of chronic pulmonary disease. The isolates were susceptible to ampicillin, imipenem, gentamicin, amikacin, and trimethoprim-sulfamethoxazole and had reduced susceptibilities to ceftriaxone, cefotaxime, minocycline, and ciprofloxacin. The MICs of amoxicillin-clavulanate were higher than that of ampicillin alone, and the bacteria produced a \u03b2-lactamase detectable only after induction with clavulanic acid. Phenotypically, the isolates could not be characterized beyond the\n            <jats:italic>Nocardia<\/jats:italic>\n            genus level. All three isolates were definitively identified as\n            <jats:italic>N<\/jats:italic>\n            .\n            <jats:italic>veterana<\/jats:italic>\n            by PCR and sequencing of the 16S rRNA gene. On the basis of their susceptibility and restriction enzyme analysis profiles, our findings indicate that they could potentially be misidentified as\n            <jats:italic>N<\/jats:italic>\n            .\n            <jats:italic>nova<\/jats:italic>\n            . These cases illustrate the pathogenic potential of this newly described species and emphasize the importance of accurate identification of\n            <jats:italic>Nocardia<\/jats:italic>\n            isolates to the species level by integrated use of phenotypic and genotypic methods.\n          <\/jats:p>","DOI":"10.1128\/jcm.41.4.1705-1709.2003","type":"journal-article","created":{"date-parts":[[2003,4,7]],"date-time":"2003-04-07T20:34:54Z","timestamp":1049747694000},"page":"1705-1709","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":51,"title":["<i>Nocardia veterana<\/i>\n            , a New Emerging Pathogen"],"prefix":"10.1128","volume":"41","author":[{"given":"Sudha","family":"Pottumarthy","sequence":"first","affiliation":[{"name":"Departments of Laboratory Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajit P.","family":"Limaye","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine"},{"name":"Infectious Diseases"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L.","family":"Prentice","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolanda B.","family":"Houze","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan R.","family":"Swanzy","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad T.","family":"Cookson","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine"},{"name":"Microbiology, University of Washington, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.35.4.847-852.1997"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.7.2.213"},{"key":"e_1_3_1_4_2","unstructured":"Brown J. M. M. M. McNeil and E. P. Desmond. 1999. Nocardia Rhodococcus Gordona Actinomadura Streptomyces and other actinomycetes of medical importance p. 370-398. In P. R. Murray E. J. Baron M. A. Pfaller F. C. Tenover and R. H. Yolken (ed.) Manual of clinical microbiology 7th ed. American Society for Microbiology Washington D.C."},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-45-2-240"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.1.158-164.2000"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-4453(90)92236-E"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1992.tb121509.x"},{"key":"e_1_3_1_9_2","first-page":"933","year":"2001","unstructured":"Gurtler, V., R. Smith, B. C. Mayall, G. Potter-Reinmann, E. Stackebrandt, and R. M. Kroppenstadt. 2001. Nocardia veterana sp. nov., isolated from human bronchial lavage. Int. J. Syst. Evol. Microbiol. 51:933-936.","journal-title":"Int. J. Syst. E"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.2.625-630.2001"},{"key":"e_1_3_1_11_2","unstructured":"Holt J. G. N. R. Krieg P. H. A. Sneath J. T. Staley and S. T. Williams (ed.). 1994. Bergey's manual of determinative bacteriology 9th ed. p. 625-650. The Williams & Wilkins Co. Baltimore Md."},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2002.tb02713.x"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.4.1467-1476.2001"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.2.789-794.2000"},{"key":"e_1_3_1_15_2","unstructured":"Land G. M. R. McGinnis J. Staneck and A. Gatson. 1991. Aerobic pathogenic Actinomycetales p. 340-360. In A. Balows W. J. Hausler Jr. K. L. Herrmann H. D. Isenberg and H. J. Shadomy (ed.) Manual of clinical microbiology 5th ed. 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