{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T01:58:24Z","timestamp":1791079104377,"version":"4.1.0"},"reference-count":22,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2003,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            CHROMagar Candida is a selective and differential chromogenic medium that has been shown to be useful for identification of\n            <jats:italic>Candida albicans<\/jats:italic>\n            ,\n            <jats:italic>Candida krusei<\/jats:italic>\n            ,\n            <jats:italic>Candida tropicalis<\/jats:italic>\n            , and perhaps\n            <jats:italic>Candida glabrata<\/jats:italic>\n            . Colony morphology and color have been well defined when CHROMagar Candida has been used to isolate yeast directly from clinical specimens, including stool, urine, respiratory, vaginal, oropharyngeal, and esophageal sources. Direct isolation of yeast on CHROMagar Candida from blood cultures has not been evaluated. We evaluated whether the color and colony characteristics produced by\n            <jats:italic>Candida<\/jats:italic>\n            spp. on CHROMagar Candida were altered when yeasts were isolated directly from blood cultures. Fifty clinical isolates of\n            <jats:italic>Candida<\/jats:italic>\n            were inoculated into aerobic and anaerobic blood culture bottles and incubated at 35\u00b0C in an automated blood culture system. When growth was detected, an aliquot was removed and plated onto CHROMagar Candida. As a control, CHROMagar Candida plates were inoculated with the same isolate of yeast grown on Sabouraud dextrose agar simultaneously. No significant difference was detected in color or colony morphology between the blood and control isolates in any of the tested organisms. All\n            <jats:italic>C. albicans<\/jats:italic>\n            (\n            <jats:italic>n<\/jats:italic>\n            = 12),\n            <jats:italic>C. tropicalis<\/jats:italic>\n            (\n            <jats:italic>n<\/jats:italic>\n            = 12),\n            <jats:italic>C. glabrata<\/jats:italic>\n            (\n            <jats:italic>n<\/jats:italic>\n            = 9), and\n            <jats:italic>C. krusei<\/jats:italic>\n            (\n            <jats:italic>n<\/jats:italic>\n            = 5) isolates exhibited the expected species-specific colony characteristics and color, whether isolated directly from blood or from control cultures. CHROMagar Candida can be reliably used for direct isolation of yeast from blood cultures. Direct isolation could allow mycology laboratories to more rapidly identify\n            <jats:italic>Candida<\/jats:italic>\n            spp., enable clinicians to more quickly make antifungal agent selections, and potentially decrease patient morbidity and mortality.\n          <\/jats:p>","DOI":"10.1128\/jcm.41.6.2629-2632.2003","type":"journal-article","created":{"date-parts":[[2003,6,5]],"date-time":"2003-06-05T19:14:27Z","timestamp":1054840467000},"page":"2629-2632","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":55,"title":["Direct Isolation of\n            <i>Candida<\/i>\n            spp. from Blood Cultures on the Chromogenic Medium CHROMagar Candida"],"prefix":"10.1128","volume":"41","author":[{"given":"Lynn L.","family":"Horvath","sequence":"first","affiliation":[{"name":"Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duane R.","family":"Hospenthal","sequence":"additional","affiliation":[{"name":"Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clinton K.","family":"Murray","sequence":"additional","affiliation":[{"name":"Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Dooley","sequence":"additional","affiliation":[{"name":"Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-47-7-623"},{"key":"e_1_3_2_3_2","first-page":"237","volume":"54","year":"1997","unstructured":"Anson, J. J., and K. D. Allen. 1997. Evaluation of CHROMagar Candida medium for the isolation and direct identification of yeast species from the female genital tract. Br. J. Biomed. Sci.54:237-239.","journal-title":"Br. J. Biomed. Sci."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.2.454-456.1996"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/167.5.1247"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.33.11.3025-3027.1995"},{"key":"e_1_3_2_7_2","first-page":"201","volume":"24","year":"1996","unstructured":"Bernal, S., E. M. Mazuelos, M. Garcia, A. I. Aller, M. A. Martinez, and M. J. Gutierrez. 1996. Evaluation of CHROMAagar Candida medium for isolation and presumptive identification of species of candida of clinical importance. Mycology24:201-204.","journal-title":"Mycology"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/520192"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02471913"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.12.4768-4770.2002"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.50.7.563"},{"key":"e_1_3_2_12_2","first-page":"568","volume":"64","year":"2001","unstructured":"Huang, L., C. Chen, C. Chou, J. Lu, W. Chi, and W. Lee. 2001. A comparison of methods for yeast identification including CHROMagar Candida, vitek system YBC and a traditional biochemical method. Chin. Med. J. (Taipei)64:568-574.","journal-title":"Chin. Med. J. (Taipei)"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.5.2015-2016.2001"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.36.10.3007-3012.1998"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.2.422-426.1999"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.43.7.1621"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.36.4.1157-1159.1998"},{"key":"e_1_3_2_18_2","unstructured":"National Committee for Clinical Laboratory Standards. 1997. Reference method for broth dilution antifungal susceptibility testing of yeasts; approved standard. NCCLS document M27-A. National Committee for Clinical Laboratory Standards Wayne Pa."},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.32.8.1923-1929.1994"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(00)00197-8"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.1.58-61.1996"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1086\/520194"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.12.3896-3900.1999"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.41.6.2629-2632.2003","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.41.6.2629-2632.2003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T02:26:10Z","timestamp":1646447170000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.41.6.2629-2632.2003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2003,6]]}},"alternative-id":["10.1128\/JCM.41.6.2629-2632.2003"],"URL":"https:\/\/doi.org\/10.1128\/jcm.41.6.2629-2632.2003","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6]]},"assertion":[{"value":"2002-12-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-03-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-06-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}