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One cat, also coinfected with feline immunodeficiency virus and \u201c<jats:italic>Candidatus<\/jats:italic>Mycoplasma haemominutum,\u201d had profound icterus and anemia which resolved after therapy, whereas a second cat was an asymptomatic carrier. Amplification and sequencing of the 18S rRNA gene, followed by phylogenetic analyses, indicated that infection was caused by<jats:italic>Babesia canis<\/jats:italic>. However, the sequences of the internal transcribed and 5.8S rRNA regions of the ribosomal operon used for subspeciation of<jats:italic>B. canis<\/jats:italic>were markedly different from the recognized subspecies of<jats:italic>B. canis<\/jats:italic>, which include<jats:italic>B. canis vogeli<\/jats:italic>,<jats:italic>B. canis canis<\/jats:italic>, and<jats:italic>B. canis rossi<\/jats:italic>. Based on phylogenetic comparisons of the 18S rRNA gene, 5.8S, and internal transcribed spacer sequences of the isolates from the cats and on the smaller sizes of the merozoite and trophozoite stages of this parasite, which distinguish it from the subspecies of<jats:italic>B. canis<\/jats:italic>present in dogs, we propose to identify the novel feline genotype of<jats:italic>B. canis<\/jats:italic>described in the present study as a new subspecies,<jats:italic>B. canis<\/jats:italic>subsp.<jats:italic>presentii<\/jats:italic>.<\/jats:p>","DOI":"10.1128\/jcm.42.1.99-105.2004","type":"journal-article","created":{"date-parts":[[2004,1,10]],"date-time":"2004-01-10T18:17:42Z","timestamp":1073758662000},"page":"99-105","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":50,"title":["Infection with a Proposed New Subspecies of<i>Babesia canis<\/i>,<i>Babesia canis<\/i>subsp.<i>presentii<\/i>, in Domestic Cats"],"prefix":"10.1128","volume":"42","author":[{"given":"Gad","family":"Baneth","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine, Hebrew University, Rehovot 76100"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin J.","family":"Kenny","sequence":"additional","affiliation":[{"name":"Department of Clinical Veterinary Science, University of Bristol, Langford, Somerset BS40 5DU, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se\u0301verine","family":"Tasker","sequence":"additional","affiliation":[{"name":"Department of Clinical Veterinary Science, University of Bristol, Langford, Somerset BS40 5DU, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yigal","family":"Anug","sequence":"additional","affiliation":[{"name":"Pathovet Veterinary Pathology Services, Kfar Bilu B 76965"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varda","family":"Shkap","sequence":"additional","affiliation":[{"name":"Division of Parasitology, Kimron Veterinary Institute, Bet Dagan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amos","family":"Levy","sequence":"additional","affiliation":[{"name":"Mevasseret Veterinary Clinic, Mevasseret Zion, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan E.","family":"Shaw","sequence":"additional","affiliation":[{"name":"Department of Clinical Veterinary Science, University of Bristol, Langford, Somerset BS40 5DU, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-26.3.392"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1006\/meth.1997.0501"},{"key":"e_1_3_1_4_2","first-page":"947","volume":"27","year":"1996","unstructured":"Bourdeau, P. 1996. 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