{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:34:38Z","timestamp":1787668478482,"version":"build-2736575974"},"reference-count":25,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A clinical evaluation was conducted in six North American centers to determine the ability of APTIMA CT (ACT) and APTIMA GC (AGC) nucleic acid amplification assays to detect\n            <jats:italic>Chlamydia trachomatis<\/jats:italic>\n            and\n            <jats:italic>Neisseria gonorrhoeae<\/jats:italic>\n            infections in 1,322 men by testing their urethral swabs and first-catch urine (FCU). The results obtained with ACT and AGC assays were compared to an infected patient status determined by testing the specimens with the APTIMA Combo 2 and the BD ProbeTec energy transfer multiplex assays. Symptoms did not influence the values. Positive and negative agreements of the ACT and AGC assays for individual specimens were high, with each comparator assay ranging between 94.3 and 100% for positives and 93.9 and 99.4% for negatives. The ACT and AGC assays performed on noninvasive specimens such as FCU effectively identified\n            <jats:italic>C. trachomatis<\/jats:italic>\n            or\n            <jats:italic>N. gonorrhoeae<\/jats:italic>\n            infections in symptomatic and asymptomatic men and should be suitable for screening male populations.\n          <\/jats:p>","DOI":"10.1128\/jcm.43.1.127-131.2005","type":"journal-article","created":{"date-parts":[[2005,1,5]],"date-time":"2005-01-05T20:14:18Z","timestamp":1104956058000},"page":"127-131","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":68,"title":["Ability of New APTIMA CT and APTIMA GC Assays To Detect\n            <i>Chlamydia trachomatis<\/i>\n            and\n            <i>Neisseria gonorrhoeae<\/i>\n            in Male Urine and Urethral Swabs"],"prefix":"10.1128","volume":"43","author":[{"given":"M. A.","family":"Chernesky","sequence":"first","affiliation":[{"name":"St. Joseph's Healthcare, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. H.","family":"Martin","sequence":"additional","affiliation":[{"name":"Louisiana State University Health Sciences Center, New Orleans, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. W.","family":"Hook","sequence":"additional","affiliation":[{"name":"University of Alabama, Birmingham, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Willis","sequence":"additional","affiliation":[{"name":"Florida State Department of Health, Jacksonville, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Jordan","sequence":"additional","affiliation":[{"name":"Magee Women's Research Institute, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Wang","sequence":"additional","affiliation":[{"name":"Gen-Probe Incorporated, San Diego"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. R.","family":"Lane","sequence":"additional","affiliation":[{"name":"Gen-Probe Incorporated, San Diego"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Fuller","sequence":"additional","affiliation":[{"name":"Wishard Memorial Hospital, Indianapolis, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Schachter","sequence":"additional","affiliation":[{"name":"University of California, San Francisco, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.31.11.3013-3016.1993"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90559-A"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/170.5.1308"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.35.4.982-984.1997"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.2.778-782.2003"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.32.10.2350-2352.1994"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.36.11.3230-3233.1998"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.1.304-309.2003"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.35.10.2628-2633.1997"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-199211000-00003"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.31.5.1209-1212.1993"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-200207000-00001"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.36.11.3122-3126.1998"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.10.3544-3549.2000"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-199401000-00003"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.OLQ.0000086600.71690.14"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.10.3092-3096.1999"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/146.6.828"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.6.1401-1406.1996"},{"key":"e_1_3_1_21_2","first-page":"429","volume":"24","year":"1997","unstructured":"Rietmeijer, C. A., K. J. Yamaguchi, C. G. Ortiz, S. A. Montstream, T. Leroux, J. M. Ehret, F. N. Judson, and J. M. Douglas. 1997. Feasibility and yield of screening urine for Chlamydia trachomatis by polymerase chain reaction among high-risk male youth in field-based and other non-clinic settings. A new strategy for sexually transmitted disease control. Sex. Transm. Dis.24:429-435.","journal-title":"A new strategy for sexually transmitted disease control. Sex. Transm. Dis."},{"key":"e_1_3_1_22_2","first-page":"47","volume":"100","year":"1984","unstructured":"Stamm, W. E., L. A. Koutsky, J. K. Benedetti, J. L. Jourden, R. C. Brunham, and K. K. Holmes. 1984. Chlamydia trachomatis urethral infections in men. Prevalence, risk factors, and clinical manifestations. Ann. Intern. Med.100:47-51.","journal-title":"Prevalence, risk factors, and clinical manifestations. Ann. Intern. 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