{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:45:58Z","timestamp":1793321158804,"version":"4.5.0"},"reference-count":19,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Two different synergy testing methods, the checkerboard and the E test methods, were used to compare the in vitro efficacies of various antimicrobial combinations against 16\n                    <jats:italic>Brucella melitensis<\/jats:italic>\n                    strains isolated from blood cultures. The rate of agreement of the E test and checkerboard methods was found to be 55%. The most concordant results were found for the streptomycin-doxycycline combination in 12 (75%) tests, in which four strains showed synergistic activity by E test and antagonistic activity by the checkerboard method and in which one strain showed antagonistic activity by both methods. Even though each of these methods uses different conditions and endpoints, the results of both methods frequently agreed.\n                  <\/jats:p>","DOI":"10.1128\/jcm.43.1.140-143.2005","type":"journal-article","created":{"date-parts":[[2005,1,5]],"date-time":"2005-01-05T15:14:18Z","timestamp":1104938058000},"page":"140-143","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":326,"title":["Synergy Tests by E Test and Checkerboard Methods of Antimicrobial Combinations against\n                    <i>Brucella melitensis<\/i>"],"prefix":"10.1128","volume":"43","author":[{"given":"Gani","family":"Orhan","sequence":"first","affiliation":[{"name":"Gaziantep University Medical Faculty, Department of Microbiology and Clinical Microbiology, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aysen","family":"Bayram","sequence":"additional","affiliation":[{"name":"Gaziantep University Medical Faculty, Department of Microbiology and Clinical Microbiology, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin","family":"Zer","sequence":"additional","affiliation":[{"name":"Gaziantep University Medical Faculty, Department of Microbiology and Clinical Microbiology, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iclal","family":"Balci","sequence":"additional","affiliation":[{"name":"Gaziantep University Medical Faculty, Department of Microbiology and Clinical Microbiology, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","unstructured":"Akal\u0131n H. 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Activity of different antimicrobial combinations against methicillin-and teicoplanin-resistant coagulase-negative staphylococci: utility of the E-test for the determination of the effects of antimicrobial combinations p. 209. Abstr. 39th Intersci. Conf. Antimicrob. Agents Chemother. American Society for Microbiology Washington D.C."},{"key":"e_1_3_1_8_2","unstructured":"Cercenado E. F. Garcia-Garotte and E. Bouza. 1996. Effect of linezolid with vancomycin against highly vancomycin resistant enterococci: utility of the E-test for the determination of the effects of antimicrobial combinations p. 210. Abstr. 39th Intersci. Conf. Antimicrob. Agents Chemother. American Society for Microbiology Washington D.C."},{"key":"e_1_3_1_9_2","first-page":"568","volume":"15","year":"2001","unstructured":"\u00c7evik, M. A. 2001. Brucelloz epidemiyolojisi. 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