{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:03:59Z","timestamp":1791313439593,"version":"4.3.1"},"reference-count":17,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2006,2,1]],"date-time":"2006-02-01T00:00:00Z","timestamp":1138752000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The emergence of a clinically daptomycin-resistant\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            isolate occurred during treatment of methicillin-resistant\n            <jats:italic>S. aureus<\/jats:italic>\n            bacteremia and probable vertebral osteomyelitis. The breakthrough isolate was indistinguishable from pretreatment daptomycin-susceptible isolates by pulsed-field gel electrophoresis. Daptomycin nonsusceptibility was confirmed by MIC and time-kill curve analyses.\n          <\/jats:p>","DOI":"10.1128\/jcm.44.2.595-597.2006","type":"journal-article","created":{"date-parts":[[2006,2,2]],"date-time":"2006-02-02T18:33:16Z","timestamp":1138905196000},"page":"595-597","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":174,"title":["Emergence of a Clinical Daptomycin-Resistant\n            <i>Staphylococcus aureus<\/i>\n            Isolate during Treatment of Methicillin-Resistant\n            <i>Staphylococcus aureus<\/i>\n            Bacteremia and Osteomyelitis"],"prefix":"10.1128","volume":"44","author":[{"given":"Francisco M.","family":"Marty","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases"},{"name":"Dana-Farber Cancer Institute"},{"name":"Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy W.","family":"Yeh","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases"},{"name":"Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine B.","family":"Wennersten","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Beth Israel Deaconess Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lata","family":"Venkataraman","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Beth Israel Deaconess Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esperanza","family":"Albano","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin P.","family":"Alyea","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Brigham &amp; Women's Hospital"},{"name":"Dana-Farber Cancer Institute"},{"name":"Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard S.","family":"Gold","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Beth Israel Deaconess Medical Center"},{"name":"Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey R.","family":"Baden","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases"},{"name":"Dana-Farber Cancer Institute"},{"name":"Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satish K.","family":"Pillai","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Beth Israel Deaconess Medical Center"},{"name":"Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/420818"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/383472"},{"key":"e_1_3_2_4_2","unstructured":"Center for Drug Evaluation and Research Food and Drug Administration. 15December 2003 posting date. NDA 21-572 Cubicin TM (daptomycin for injection). [Online.] http:\/\/www.fda.gov\/cder\/foi\/nda\/2003\/21-572_Cubicin_Microbr_P2.pdf\n. Accessed 12 June 2005."},{"key":"e_1_3_2_5_2","unstructured":"Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing; fifteenth informational supplement M100-S15. Clinical and Laboratory Standards Institute Wayne Pa."},{"key":"e_1_3_2_6_2","unstructured":"Cubist Pharmaceuticals Inc. 2003 posting date. Cubicin TM (daptomycin for Injection) prescriber information. [Online.] http:\/\/www.cubicin.com\/documents\/cubicin_large_pi.pdf\n. Accessed 12 June 2005."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/107662903322762833"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.12.4665-4672.2004"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.33.5.689"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1086\/428616"},{"key":"e_1_3_2_11_2","first-page":"563","year":"1993","unstructured":"Maslow, J., A. M. Slutsky, and R. D. Arbeit. 1993. The application of pulsed-field gel electrophoresis to molecular epidemiology, p. 563-572. In D. H. Persing, T. F. Smith, F. C. Tenover, and J. White (ed.), Diagnostic molecular microbiology: principles and applications. American Society for Microbiology, Washington, D.C.","journal-title":"Diagnostic molecular microbiology: principles and applications"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2004.00070.x"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.36.5.1109"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1086\/430352"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.6.1799-1802.2001"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkh546"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkh143"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.33.9.2233-2239.1995"}],"container-title":["Journal of Clinical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.44.2.595-597.2006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JCM.44.2.595-597.2006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T04:58:24Z","timestamp":1646456304000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JCM.44.2.595-597.2006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["10.1128\/JCM.44.2.595-597.2006"],"URL":"https:\/\/doi.org\/10.1128\/jcm.44.2.595-597.2006","relation":{},"ISSN":["0095-1137","1098-660X"],"issn-type":[{"value":"0095-1137","type":"print"},{"value":"1098-660X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2]]},"assertion":[{"value":"2005-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-11-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2006-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}