{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T07:09:14Z","timestamp":1790492954926,"version":"4.1.0"},"reference-count":19,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Clin Microbiol"],"published-print":{"date-parts":[[2006,3]]},"abstract":"ABSTRACT<\/jats:title>\n \n Many studies investigating\n Mycobacterium avium<\/jats:italic>\n subsp.\n paratuberculosis<\/jats:italic>\n in Crohn's disease have used molecular detection of IS\n 900<\/jats:italic>\n in clinical samples, but some have described polymorphisms in IS\n 900<\/jats:italic>\n as variants of this organism. Analysis of 23\n M. avium<\/jats:italic>\n subsp.\n paratuberculosis<\/jats:italic>\n isolates revealed that IS\n 900<\/jats:italic>\n is highly conserved, with only two sequevars distinguishing sheep and cattle lineages. Amplification of IS\n 900<\/jats:italic>\n -like sequences is not sufficient as a proxy for\n M. avium<\/jats:italic>\n subsp.\n paratuberculosis<\/jats:italic>\n .\n <\/jats:p>","DOI":"10.1128\/jcm.44.3.1081-1083.2006","type":"journal-article","created":{"date-parts":[[2006,3,3]],"date-time":"2006-03-03T22:28:19Z","timestamp":1141424899000},"page":"1081-1083","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":43,"title":["Insertion Sequence IS\n 900<\/i>\n Revisited"],"prefix":"10.1128","volume":"44","author":[{"given":"Makeda","family":"Semret","sequence":"first","affiliation":[{"name":"McGill University Health Center, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine Y.","family":"Turenne","sequence":"additional","affiliation":[{"name":"McGill University Health Center, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel A.","family":"Behr","sequence":"additional","affiliation":[{"name":"McGill University Health Center, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.045526"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2005.10.004"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-146-9-2185"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.7.2915-2923.2003"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1006\/mcpr.1999.0275"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2002.tb11142.x"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/17.22.9063"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.3.489-512.2001"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/5.2.150"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0505662102"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17058-X"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.71.4.2130-2139.2005"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.5.665"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.41415.x"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.8.3704-3712.2005"},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","unstructured":"Semret M. C. Y. Turenne P. de Haas D. M. Collins and M. A. Behr. 2006. Differentiating host-associated variants of Mycobacterium avium species by PCR for detection of large sequence polymorphisms. J. Clin. Microbiol. 44:881-887.","DOI":"10.1128\/JCM.44.3.881-887.2006"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2005.04.002"},{"key":"e_1_3_2_19_2","doi-asserted-by":"crossref","unstructured":"Turenne C. Y. M. Semret D. V. Cousins D. M. Collins and M. A. Behr. 2006. Sequencing of hsp65 distinguishes among subsets of the Mycobacterium avium complex. J. Clin. 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