{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:22:32Z","timestamp":1787836952211,"version":"build-2784847793"},"reference-count":11,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:00:00Z","timestamp":1787788800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Microbiol Biol Educ."],"published-print":{"date-parts":[[2026,8,27]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>Artificial intelligence (AI) has transformed various industries, and education is no exception. This paper details how AI can be utilized to support the development of an interactive, choose-your-own-adventure learning activity for pre-health students. With ChatGPT assistance, we identified and implemented the open-source platform Twine to create a branching, scenario-based activity focused on sexually transmitted diseases (STDs), allowing students to engage with clinical decision-making and apply course concepts. Additionally, ChatGPT\u2019s natural language processing capabilities allowed educators to create a script-based learning experience informed by prior student feedback, providing students with immediate, targeted feedback and support. This study describes how AI was used to develop a novel learning activity that encourages student engagement and application of course concepts. Students who piloted this activity in an upper-division course reported the activity to be an effective and engaging learning experience that helped them apply course content to real-life scenarios. Importantly, the use of AI helped streamline the development of this activity, lowering barriers to creating complex educational activities that may otherwise be difficult to implement. Here, we demonstrate how AI can be leveraged to support the development of interactive, scenario-based learning activities and provide practical guidance for instructors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/jmbe.00323-25","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T13:40:31Z","timestamp":1784641231000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Harnessing AI and chatbots to develop an interactive learning activity: student perceptions and outcomes"],"prefix":"10.1128","volume":"27","author":[{"given":"Usean J.","family":"Redic","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04gyf1771","id-type":"ROR","asserted-by":"publisher"}],"name":"Human Biology Program, Department of Neurobiology and Behavior, University of California, Irvine","place":["Irvine, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deavin F.","family":"Tendean","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04gyf1771","id-type":"ROR","asserted-by":"publisher"}],"name":"Human Biology Program, Department of Neurobiology and Behavior, University of California, Irvine","place":["Irvine, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7172-7707","authenticated-orcid":true,"given":"Andrea C.","family":"Nicholas","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04gyf1771","id-type":"ROR","asserted-by":"publisher"}],"name":"Human Biology Program, Department of Neurobiology and Behavior, University of California, Irvine","place":["Irvine, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/10494820.2023.2253858"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcpdig.2023.05.004"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12909-023-04231-2"},{"key":"e_1_3_3_5_2","unstructured":"Gonorrhea: symptoms treatment causes and more. 2025 Available from: https:\/\/www.healthline.com\/health\/gonorrhea"},{"key":"e_1_3_3_6_2","unstructured":"Trachoma. 2020. Available from: https:\/\/www.mayoclinic.org\/diseases-conditions\/trachoma\/symptoms-causes\/syc-20378505"},{"key":"e_1_3_3_7_2","unstructured":"World Health Organization (WHO). 2021 Available from: https:\/\/www.who.int\/"},{"key":"e_1_3_3_8_2","unstructured":"Sexually transmitted diseases - Your guide to STDs. 2022. Available from: https:\/\/www.webmd.com\/sexual-conditions\/sexual-health-stds"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-199904001-00002"},{"key":"e_1_3_3_10_2","volume-title":"Biological sciences","author":"Freeman S","year":"2014","unstructured":"Freeman S. 2014. Biological sciences. Pearson."},{"key":"e_1_3_3_11_2","first-page":"16","article-title":"Overcoming ChatGPTs inaccuracies with pre-trained AI prompt engineering sequencing process","volume":"3","author":"Poola I","year":"2023","unstructured":"Poola I. 2023. Overcoming ChatGPTs inaccuracies with pre-trained AI prompt engineering sequencing process. IJTES 3:16\u201319.","journal-title":"IJTES"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.39238"}],"container-title":["Journal of Microbiology &amp; Biology Education"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jmbe.00323-25","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jmbe.00323-25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:02:35Z","timestamp":1787835755000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jmbe.00323-25"}},"subtitle":[],"editor":[{"given":"Logan","family":"McCarty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,8,27]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,8,27]]}},"alternative-id":["10.1128\/jmbe.00323-25"],"URL":"https:\/\/doi.org\/10.1128\/jmbe.00323-25","relation":{},"ISSN":["1935-7877","1935-7885"],"issn-type":[{"value":"1935-7877","type":"print"},{"value":"1935-7885","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,27]]},"assertion":[{"value":"2025-12-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00323-25"}}