{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:23:55Z","timestamp":1792131835303,"version":"4.4.0"},"reference-count":99,"publisher":"American Society for Microbiology","issue":"17","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100000923","name":"Department of Education and Training | Australian Research Council","doi-asserted-by":"publisher","award":["DP150101782"],"award-info":[{"award-number":["DP150101782"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>\n                    The mosquito\n                    <jats:named-content content-type=\"genus-species\">Aedes aegypti<\/jats:named-content>\n                    transmits a number of arthropod-borne viruses (arboviruses), such as dengue virus and Zika virus. Mosquitoes also harbor insect-specific viruses that may affect replication of pathogenic arboviruses in their body. Currently, however, there are only a few insect-specific viruses described from\n                    <jats:named-content content-type=\"genus-species\">A. aegypti<\/jats:named-content>\n                    in the literature. Here, we characterize a novel negative-strand virus, AeAV. Meta-analysis of\n                    <jats:named-content content-type=\"genus-species\">A. aegypti<\/jats:named-content>\n                    samples showed that it is present in\n                    <jats:named-content content-type=\"genus-species\">A. aegypti<\/jats:named-content>\n                    mosquitoes worldwide and is vertically transmitted.\n                    <jats:named-content content-type=\"genus-species\">Wolbachia<\/jats:named-content>\n                    -transinfected mosquitoes are currently being used in biocontrol, as they effectively block transmission of several positive-sense RNA viruses in mosquitoes. Our results demonstrate that\n                    <jats:named-content content-type=\"genus-species\">Wolbachia<\/jats:named-content>\n                    enhances the replication of AeAV and modestly reduces dengue virus replication in a cell line model. This study expands our understanding of the virome in\n                    <jats:named-content content-type=\"genus-species\">A. aegypti<\/jats:named-content>\n                    as well as providing insight into the complexity of the\n                    <jats:named-content content-type=\"genus-species\">Wolbachia<\/jats:named-content>\n                    virus restriction phenotype.\n                  <\/jats:p>","DOI":"10.1128\/jvi.00224-18","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T07:41:40Z","timestamp":1530085300000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":82,"title":["Aedes Anphevirus: an Insect-Specific Virus Distributed Worldwide in Aedes aegypti Mosquitoes That Has Complex Interplays with Wolbachia and Dengue Virus Infection in Cells"],"prefix":"10.1128","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9238-1952","authenticated-orcid":false,"given":"Rhys","family":"Parry","sequence":"first","affiliation":[{"name":"Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, Brisbane, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7885-6544","authenticated-orcid":false,"given":"Sassan","family":"Asgari","sequence":"additional","affiliation":[{"name":"Australian Infectious Disease Research Centre, School of Biological Sciences, The University of Queensland, Brisbane, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","first-page":"166","article-title":"Spatial distribution of Aedes aegypti and Aedes albopictus in relation to geo-ecological features in South Andaman, Andaman and Nicobar Islands, India","volume":"3","author":"Shriram AN","year":"2017","unstructured":"Shriram AN, Sivan A, Sugunan AP. 2017. Spatial distribution of Aedes aegypti and Aedes albopictus in relation to geo-ecological features in South Andaman, Andaman and Nicobar Islands, India. Bull Entomol Res 3:166\u2013174.","journal-title":"Bull Entomol Res"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature12060"},{"key":"e_1_3_3_4_2","unstructured":"European Centre for Disease Prevention and Control. 2015. Rapid risk assessment: Zika virus epidemic in the Americas: potential association with microcephaly and Guillain-Barr\u00e9 syndrome. 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