{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:27:13Z","timestamp":1791322033264,"version":"4.3.1"},"reference-count":39,"publisher":"American Society for Microbiology","issue":"17","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>Pathogenic circulating vaccine-derived polioviruses (cVDPVs) have become a major obstacle to the successful completion of the global polio eradication program. Most cVDPVs are recombinant between the oral poliovirus vaccine (OPV) and human enterovirus species C (HEV-C). To study the role of HEV-C sequences in the phenotype of cVDPVs, we generated a series of recombinants between a Madagascar cVDPV isolate and its parental OPV type 2 strain. Results indicated that the HEV-C sequences present in this cVDPV contribute to its characteristics, including pathogenicity, suggesting that interspecific recombination contributes to the phenotypic biodiversity of polioviruses and may favor the emergence of cVDPVs.<\/jats:p>","DOI":"10.1128\/jvi.00239-08","type":"journal-article","created":{"date-parts":[[2008,6,26]],"date-time":"2008-06-26T00:46:13Z","timestamp":1214441173000},"page":"8927-8932","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":29,"title":["Impact of Exogenous Sequences on the Characteristics of an Epidemic Type 2 Recombinant Vaccine-Derived Poliovirus"],"prefix":"10.1128","volume":"82","author":[{"given":"Franck B.","family":"Riquet","sequence":"first","affiliation":[{"name":"Unite\u0301 de Biologie des Virus Ente\u0301riques"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Blanchard","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Biologie des Virus Ente\u0301riques"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Jegouic","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Biologie des Virus Ente\u0301riques"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Balanant","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Biologie des Virus Ente\u0301riques"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Guillot","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Biologie des Virus Ente\u0301riques"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Anne","family":"Vibet","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Pharmacoe\u0301pide\u0301miologie et Maladies Infectieuses, Institut Pasteur, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mala","family":"Rakoto-Andrianarivelo","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Virologie Me\u0301dicale, Institut Pasteur de Madagascar, Antananarivo, Madagascar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Delpeyroux","sequence":"additional","affiliation":[{"name":"Unite\u0301 de Biologie des Virus Ente\u0301riques"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","first-page":"211","volume":"299","year":"2006","unstructured":"Agol, V. I. 2006. Molecular mechanisms of poliovirus variation and evolution. Curr. Top. Microbiol. Immunol.299:211-259.","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.80784-0"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.20.12650-12657.2005"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.16.8973-8984.2003"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.2.1062-1070.2005"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2004.04.026"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.65.5.2707-2710.1991"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/525049"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.69.9.5278-5286.1995"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.2.681-688.1994"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0700451104"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1068284"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-56-2-337"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.58.030603.123625"},{"key":"e_1_3_2_16_2","first-page":"16","volume":"82","year":"2004","unstructured":"Kew, O. M., P. F. Wright, V. I. Agol, F. Delpeyroux, H. Shimizu, N. Nathanson, and M. A. Pallansch. 2004. Circulating vaccine-derived polioviruses: current state of knowledge. Bull. W. H. O.82:16-23.","journal-title":"Bull. W. H. O."},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-2126(97)00249-9"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1086\/506359"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(92)90565-7"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1993.1003"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.7.3001-3010.2000"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.24.13839-13847.2004"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.19.9900-9909.2002"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-73-12-3065"},{"key":"e_1_3_2_25_2","first-page":"151","volume":"22","year":"1950","unstructured":"Pizzi, M. 1950. Sampling variation of the fifty percent end-point, determined by the Reed-Muench (Behrens) method. Hum. Biol.22:151-190.","journal-title":"Hum. Biol."},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2005.09.015"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0030191"},{"key":"e_1_3_2_28_2","first-page":"493","volume":"27","year":"1938","unstructured":"Reed, L. J., and M. Muench. 1938. A simple method for estimating fifty percent endpoints. Am. J. Hyg.27:493-497.","journal-title":"Am. J. Hyg."},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.65.3.1377-1382.1991"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1999.9718"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.22.10371-10380.2000"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0907.020692"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.24.13512-13521.2004"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.10.3729-3734.2000"},{"key":"e_1_3_2_35_2","first-page":"426","volume":"11","year":"1994","unstructured":"Sutter, R. W., and R. Prevots. 1994. Vaccine-associated paralytic poliomyelitis among immunodeficient persons. Infect. Med.11:426-438.","journal-title":"Infect. Med."},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.67.8.4630-4638.1993"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.8.2330"},{"key":"e_1_3_2_38_2","first-page":"337","volume":"82","year":"2007","unstructured":"WHO. 2007. Global update on vaccine-derived polioviruses, January 2006-August 2007. Wkly. Epidemiol. Rec.82:337-344.","journal-title":"Wkly. Epidemiol. Rec."},{"key":"e_1_3_2_39_2","first-page":"398","volume":"81","year":"2006","unstructured":"WHO. 2006. Vaccine-derived polioviruses\u2014update. Wkly. Epidemiol. Rec.81:398-404.","journal-title":"Wkly. Epidemiol. Rec."},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.15.8366-8377.2003"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.00239-08","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.00239-08","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T11:57:44Z","timestamp":1646481464000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JVI.00239-08"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":39,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["10.1128\/JVI.00239-08"],"URL":"https:\/\/doi.org\/10.1128\/jvi.00239-08","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9]]},"assertion":[{"value":"2008-02-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-06-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-09-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}