{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T17:53:28Z","timestamp":1783706008137,"version":"3.55.0"},"reference-count":48,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["Grant31873018"],"award-info":[{"award-number":["Grant31873018"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Industrial chain Fund of Hongshan Laboratory","award":["NO. 2022hszd005"],"award-info":[{"award-number":["NO. 2022hszd005"]}]},{"name":"The earmarked fund for CARS-41","award":["NO. CARS-41"],"award-info":[{"award-number":["NO. CARS-41"]}]},{"DOI":"10.13039\/501100017274","name":"The Central Public Interest Scientific Institution Basal Research Fund","doi-asserted-by":"publisher","award":["National Data Center of Animal Health"],"award-info":[{"award-number":["National Data Center of Animal Health"]}],"id":[{"id":"10.13039\/501100017274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"MOE | Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["140422008"],"award-info":[{"award-number":["140422008"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2023,5,31]]},"abstract":"<jats:p>\n            As an attractive immunization approach for chickens,\n            <jats:italic>in ovo<\/jats:italic>\n            vaccination can induce a considerable degree of protection by the time of hatching, provide support in closing the window in which birds are susceptible to infection, facilitate fast and uniform vaccine delivery, and reduce labor costs by the use of mechanized injectors. The commercial live Newcastle disease virus (NDV) vaccine strains are not safe for\n            <jats:italic>in ovo<\/jats:italic>\n            vaccination and cause the death of chicken embryos.\n          <\/jats:p>","DOI":"10.1128\/jvi.00324-23","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T14:02:39Z","timestamp":1681308159000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Identification of Embryonic Chicken Proteases Activating Newcastle Disease Virus and Their Roles in the Pathogenicity of Virus Used as\n            <i>In Ovo<\/i>\n            Vaccine"],"prefix":"10.1128","volume":"97","author":[{"given":"Helong","family":"Feng","sequence":"first","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Division of Veterinary Pathology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lun","family":"Yao","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Zeng","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liren","family":"Jiang","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Shang","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongcai","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zichen","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongchun","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingqing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangfei","family":"Ren","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5060-1486","authenticated-orcid":true,"given":"Tengfei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongrong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunqing","family":"Guo","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Lu","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Hu","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenting","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0216-2129","authenticated-orcid":true,"given":"Chan","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Avian Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huabin","family":"Shao","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guofu","family":"Cheng","sequence":"additional","affiliation":[{"name":"Division of Veterinary Pathology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingping","family":"Luo","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"},{"name":"Hubei Hongshan Laboratory, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3580-6963","authenticated-orcid":true,"given":"Guoyuan","family":"Wen","sequence":"additional","affiliation":[{"name":"Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China"},{"name":"Key Laboratory of Prevention and Control Agents for Animal Bacteriosis, Ministry of Agriculture, Wuhan, China"},{"name":"Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Wuhan, China"},{"name":"Hubei Hongshan Laboratory, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.5582\/bst.2019.01070"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/03079457409353840"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/03079457.2010.544289"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7278459"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.78.7.3733-3741.2004"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.05679-11"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0172812"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/76.1.165"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3382\/ps\/pey081"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2007.01.115"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2005.10.020"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1637\/9870-080311-Reg.1"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1637\/9980-110311-Reg.1"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.01.020"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11262-012-0871-1"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2020.01.006"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.812289"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2014.02.016"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2018.02.006"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky1049"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx1134"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-022-02435-y"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcb.2015.05.013"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.3390\/v13061081"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00676-08"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2020.607479"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abc3582"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01118-06"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02205-08"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00306-12"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01430-19"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01427-14"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.440362"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00065-15"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.62.1.354-356.1988"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183923"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1999.tb02384.x"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.628636"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00649-19"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009225"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/med.21475"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1080\/13543776.2021.1857726"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells9112377"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1039\/d0sc05064d"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2015.07.001"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2011.07.014"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13568-021-01196-7"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.000067"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00324-23","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00324-23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T13:03:51Z","timestamp":1685538231000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jvi.00324-23"}},"subtitle":[],"editor":[{"given":"Rebecca Ellis","family":"Dutch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,5,31]]},"references-count":48,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5,31]]}},"alternative-id":["10.1128\/jvi.00324-23"],"URL":"https:\/\/doi.org\/10.1128\/jvi.00324-23","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,31]]},"assertion":[{"value":"2023-03-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00324-23"}}