{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:16:43Z","timestamp":1783037803220,"version":"3.54.6"},"reference-count":69,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000097","name":"HHS | NIH | National Center for Research Resources","doi-asserted-by":"publisher","award":["5P20RR016469"],"award-info":[{"award-number":["5P20RR016469"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"HHS | NIH | National Center for Research Resources","doi-asserted-by":"publisher","award":["8P20GM103427"],"award-info":[{"award-number":["8P20GM103427"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2023,5,31]]},"abstract":"<jats:p>Human enteroviruses, which include five different species and over 100 serotypes, are responsible for diseases ranging from mild respiratory infections to serious infections of pancreas, heart, and neural tissue. All enteroviral RNA genomes have a long and highly structured 5\u2032 untranslated region (5\u2032 UTR) containing an internal ribosome entry site (IRES).<\/jats:p>","DOI":"10.1128\/jvi.00448-23","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T10:00:32Z","timestamp":1681898432000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Role of RNA Domain Structure and Orientation in the Coxsackievirus B3 Virulence Phenotype"],"prefix":"10.1128","volume":"97","author":[{"given":"Lydia","family":"Phillips","sequence":"first","affiliation":[{"name":"Biology Department, University of Nebraska at Omaha, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7744-7658","authenticated-orcid":true,"given":"William E.","family":"Tapprich","sequence":"additional","affiliation":[{"name":"Biology Department, University of Nebraska at Omaha, Omaha, Nebraska, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20470"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2828(90)91476-n"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.1997.tb02739.x"},{"key":"e_1_3_2_5_2","first-page":"454","volume-title":"Fields virology","author":"Racaniello VR","year":"2013","unstructured":"Racaniello VR. 2013. Picornaviridae: the viruses and their replication, p 454\u2013489. In Knipe DM, Howley PM (ed), Fields virology, 6th ed. Lippincott Williams & Wilkins, Philadelphia, PA.","edition":"6"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-018-0297-1"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2017.01.010"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/2211-5463.13400"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2015.04.008"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01288-19"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/334320a0"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2009.07.039"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1086\/374877"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.74.10.4787-4794.2000"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/314548a0"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.71.5.3986-3991.1997"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku706"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(89)90261-1"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-1702(97)00096-8"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(88)90656-3"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01327-06"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.76.23.12097-12111.2002"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.80424-0"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9071(200009)62:1%3C70::AID-JMV11%3E3.0.CO;2-R"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.249"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja2104075"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja0704028"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1261\/rna.061945.117"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.8b01218"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3029"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx386"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20174116"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.14.6472-6481.2001"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027082"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-2126(04)00008-5"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi200524n"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.8b00575"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.0c11365"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.4161\/rna.25107"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv141"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(90)90170-j"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00516-07"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1002\/embj.201386124"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa519"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.3001"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biophys.26.1.113"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2020.574485"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1261\/rna.075341.120"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.csbj.2020.08.017"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.74.5.2219-2226.2000"},{"key":"e_1_3_2_51_2","first-page":"882","article-title":"Two functional complexes formed by KH domain containing proteins with the 5\u2019 noncoding region of poliovirus RNA","volume":"3","author":"Gamarnik AV","year":"1997","unstructured":"Gamarnik AV, Andino R. 1997. Two functional complexes formed by KH domain containing proteins with the 5\u2019 noncoding region of poliovirus RNA. RNA 3:882\u2013892.","journal-title":"RNA"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601494"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0900153106"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.82463-0"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232415497"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.77.6.3353-3359.2003"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi048973p"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1261\/rna.313707"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2009.02.010"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.12.15.2293"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2015.00233"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00011-08"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02569-09"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18594-3"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2015.103"},{"key":"e_1_3_2_66_2","first-page":"11 2 1","article-title":"RNA secondary structure prediction","volume":"67","author":"Mathews DH","year":"2016","unstructured":"Mathews DH, Turner DH, Watson RM. 2016. RNA secondary structure prediction. Curr Protoc Nucleic Acids Chem 67:11 2 1\u201311 2 19.","journal-title":"Curr Protoc Nucleic Acids Chem"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx815"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2017.06.039"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-12-108"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.3390\/v12090919"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00448-23","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00448-23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T09:05:05Z","timestamp":1685523905000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jvi.00448-23"}},"subtitle":[],"editor":[{"given":"Susana","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,5,31]]},"references-count":69,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5,31]]}},"alternative-id":["10.1128\/jvi.00448-23"],"URL":"https:\/\/doi.org\/10.1128\/jvi.00448-23","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,31]]},"assertion":[{"value":"2023-03-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00448-23"}}