{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T17:41:52Z","timestamp":1769881312707,"version":"3.49.0"},"reference-count":79,"publisher":"American Society for Microbiology","issue":"20","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/AuthorWarrantyLicense.v1"},{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["HHSN272201400008C"],"award-info":[{"award-number":["HHSN272201400008C"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","award":["5030-32000-120-00-D"],"award-info":[{"award-number":["5030-32000-120-00-D"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","award":["5030-32000-128-28-A"],"award-info":[{"award-number":["5030-32000-128-28-A"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","award":["5030-32000-120-26-I"],"award-info":[{"award-number":["5030-32000-120-26-I"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","award":["5030-32000-120-80-I"],"award-info":[{"award-number":["5030-32000-120-80-I"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","award":["0500-00093-001-00-D"],"award-info":[{"award-number":["0500-00093-001-00-D"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2021,9,27]]},"abstract":"<jats:p>Antibodies inhibiting the neuraminidase (NA) of IAV reduce clinical disease, virus shedding, and transmission, particularly in the absence of neutralizing immunity against hemagglutinin. To understand antibody recognition of the genetically diverse NA in U.S. swine IAV, we characterized the antigenic diversity of N2 from swine and humans.<\/jats:p>","DOI":"10.1128\/jvi.00632-21","type":"journal-article","created":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T16:55:33Z","timestamp":1628700933000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Evolution and Antigenic Advancement of N2 Neuraminidase of Swine Influenza A Viruses Circulating in the United States following Two Separate Introductions from Human Seasonal Viruses"],"prefix":"10.1128","volume":"95","author":[{"given":"Bryan S.","family":"Kaplan","sequence":"first","affiliation":[{"name":"Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3138-5535","authenticated-orcid":true,"given":"Tavis K.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Chang","sequence":"additional","affiliation":[{"name":"Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jefferson","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6569-5689","authenticated-orcid":true,"given":"Daniel","family":"Perez","sequence":"additional","affiliation":[{"name":"Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Pathobiology and Population Sciences, The Royal Veterinary College, University of London, London, Hertfordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4953-7285","authenticated-orcid":true,"given":"Amy L.","family":"Vincent","sequence":"additional","affiliation":[{"name":"Virus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.69.2.1099-1106.1995"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-33-1-159"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(74)90276-1"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02537-14"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-10-321"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110026"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.10.4075-4084.2005"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-3542(00)00123-6"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2011.08.006"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/129.4.411"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(82)90510-4"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(88)90640-x"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02275-15"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-017-0011-8"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01588-17"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01203-13"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02556-14"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00417-16"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.03.030"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv195"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)92196-X"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02281-16"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.043059-0"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1113801108"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02332-17"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12559"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3527(08)00403-X"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00459-15"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.10.8851-8856.1999"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.74.18.8243-8251.2000"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2004.02.015"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.3.1123-1126.2006"},{"key":"e_1_3_3_34_2","doi-asserted-by":"crossref","unstructured":"Zeller MA Chang J Vincent AL Gauger PC Anderson TK. 2020. Coordinated evolution between N2 neuraminidase and H1 and H3 hemagglutinin genes increase influenza A virus genetic diversity in swine. BioRxiv 10.1101\/2020.05.29.123828.","DOI":"10.1101\/2020.05.29.123828"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-018-2408-7"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.06.001"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.01.082"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1177\/0300985812439724"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000468"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6742a1"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00665-18"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1119945109"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03805-13"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01002-16"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12610"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02434-13"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02625-12"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1128\/MRA.01203-18"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a038737"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00391a020"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(85)90157-6"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.76.23.12274-12280.2002"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2005.10.014"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2005.11.061"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1101\/sqb.1989.054.01.032"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2019.10.002"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.08.072"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(84)90114-4"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(82)90244-6"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1038\/emi.2012.33"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit272"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit649"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis500"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.2807\/ese.17.04.20066-en"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01444-18"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2016.11.026"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz017"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2018.03.025"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw857"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst010"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msu300"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msaa015"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0046378"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01503-10"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2014.09.003"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-2659.2009.00094.x"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-0346-8_24"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.027557-0"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1097211"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-24277-4"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.00632-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.00632-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T16:31:17Z","timestamp":1646497877000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JVI.00632-21"}},"subtitle":[],"editor":[{"given":"Colin R.","family":"Parrish","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,9,27]]},"references-count":79,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2021,9,27]]}},"alternative-id":["10.1128\/JVI.00632-21"],"URL":"https:\/\/doi.org\/10.1128\/jvi.00632-21","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,27]]},"assertion":[{"value":"2021-04-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00632-21"}}