{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:34:30Z","timestamp":1790948070408,"version":"4.1.0"},"reference-count":51,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T00:00:00Z","timestamp":1690416000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T00:00:00Z","timestamp":1690416000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"National Program on Key Research Project of China","award":["2021YFD1800300"],"award-info":[{"award-number":["2021YFD1800300"]}]},{"DOI":"10.13039\/501100001809","name":"MOST | National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32072841"],"award-info":[{"award-number":["32072841"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2023,7,27]]},"abstract":"<jats:p>Although FMDV is an important virulent infectious disease virus, few reports have addressed its relationship with pyroptosis or pyroptosis factors, and most studies focus on the immune escape mechanism of FMDV. GSDME (DFNA5) was initially identified as being associated with deafness disorders.<\/jats:p>","DOI":"10.1128\/jvi.00686-23","type":"journal-article","created":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T15:16:28Z","timestamp":1687878988000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":18,"title":["Foot-and-Mouth Disease Virus Induces Porcine Gasdermin E-Mediated Pyroptosis through the Protease Activity of 3C\n            <sup>pro<\/sup>"],"prefix":"10.1128","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5019-9562","authenticated-orcid":false,"given":"Xujiao","family":"Ren","sequence":"first","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"},{"name":"College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengge","family":"Yin","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"},{"name":"College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiongqiong","family":"Zhao","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"},{"name":"College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixuan","family":"Zheng","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"},{"name":"College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyuan","family":"Wang","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"},{"name":"College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9138-692X","authenticated-orcid":true,"given":"Zengjun","family":"Lu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangmin","family":"Li","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"},{"name":"College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"},{"name":"The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, Hubei, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3120-2556","authenticated-orcid":false,"given":"Ping","family":"Qian","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"},{"name":"College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, People\u2019s Republic of China"},{"name":"The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, Hubei, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04670-5"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-1702(02)00263-0"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1023\/a:1011178626292"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.17.2.465-493.2004"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2006.07.006"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.737031"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/v12121348"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00803-20"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10121566"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells10020271"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2016.10.004"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2015.139"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01504"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.05.058"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.37854"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1421699112"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms9761"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature22393"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaz7548"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2071-9"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2022.101850"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.73792"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-020-00599-1"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-019-01551-x"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27813"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.2001030"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01069-17"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2017.03.009"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf2154"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2015.124"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature15514"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2020.07.012"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.00238"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-020-00630-3"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-020-00946-7"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1995.0030"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1042\/BST0391371"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2018.05.046"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2013.12.012"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2017.01.003"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.02739-21"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2021.101480"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3002103"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2017.05.005"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2017.24"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature15541"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-021-00916-7"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2022.11.006"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12250-020-00230-5"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.1c00203"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21334"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00686-23","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00686-23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T13:03:22Z","timestamp":1690463002000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jvi.00686-23"}},"subtitle":[],"editor":[{"given":"Rebecca Ellis","family":"Dutch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,7,27]]},"references-count":51,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7,27]]}},"alternative-id":["10.1128\/jvi.00686-23"],"URL":"https:\/\/doi.org\/10.1128\/jvi.00686-23","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,27]]},"assertion":[{"value":"2023-05-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00686-23"}}