{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:38:51Z","timestamp":1790761131743,"version":"4.1.0"},"reference-count":66,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T00:00:00Z","timestamp":1655856000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T00:00:00Z","timestamp":1655856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["CB-2015-1 number 254461"],"award-info":[{"award-number":["CB-2015-1 number 254461"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["PRONAII 302979 A1-S- 9005"],"award-info":[{"award-number":["PRONAII 302979 A1-S- 9005"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2022,6,22]]},"abstract":"<jats:p>Dengue is the most important mosquito-borne viral disease to humans. Dengue virus NS1 is a multifunctional protein essential for replication and modulation of innate immunity.<\/jats:p>","DOI":"10.1128\/jvi.00704-22","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T13:02:02Z","timestamp":1654174922000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["The Dengue Virus Nonstructural Protein 1 (NS1) Interacts with the Putative Epigenetic Regulator DIDO1 to Promote Flavivirus Replication in Mosquito Cells"],"prefix":"10.1128","volume":"96","author":[{"given":"Gerson I.","family":"Caraballo","sequence":"first","affiliation":[{"name":"Department of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies (CINVESTAV-IPN), Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romel","family":"Rosales","sequence":"additional","affiliation":[{"name":"Department of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies (CINVESTAV-IPN), Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercedes","family":"Viettri","sequence":"additional","affiliation":[{"name":"Department of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies (CINVESTAV-IPN), Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Manuel","family":"Castillo","sequence":"additional","affiliation":[{"name":"Department of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies (CINVESTAV-IPN), Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymundo","family":"Cruz","sequence":"additional","affiliation":[{"name":"Department of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies (CINVESTAV-IPN), Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5338-260X","authenticated-orcid":true,"given":"Siyuan","family":"Ding","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA"},{"name":"VA Palo Alto Health Care System, Department of Veterans Affairs, Palo Alto, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2128-9080","authenticated-orcid":true,"given":"Harry B.","family":"Greenberg","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA"},{"name":"VA Palo Alto Health Care System, Department of Veterans Affairs, Palo Alto, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4790-7681","authenticated-orcid":true,"given":"Juan E.","family":"Ludert","sequence":"additional","affiliation":[{"name":"Department of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies (CINVESTAV-IPN), Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/v9050097"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12250-019-00086-4"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2008.232"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/v9040091"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2015.09.016"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.07.005"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002642"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/21.11.2757"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M104248200"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/v9030042"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2013.03.008"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-018-0462-0"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1996.0307"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.71.9.6650-6661.1997"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1998.9156"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1322036111"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1017338108"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature22365"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.11.094"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-016-0590-7"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-virology-101416-041848"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00275-18"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2015.11.020"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2017.12.014"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000881"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01985-18"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201112098"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/cpps.51"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep00075"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03819-2"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq537"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki005"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.1239303"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.11.028"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01342-15"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2016.04.008"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2015.05.017"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.23.9.3216-3225.2003"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2017.02.013"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.486290"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.001134"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz235"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp101"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00554-17"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-020-04294-w"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20092545"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1100750"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M111.012187"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.6422"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2008.04.165"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-11-380"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000954"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005841"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2012.115"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2016.11.001"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000872"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-017-1934-z"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0194664"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.4.1295-1304.2006"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1408.080287"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abc0476"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2075"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E15-12-0844"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA118.006004"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1621"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0550-8"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00704-22","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00704-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T13:01:34Z","timestamp":1655902894000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jvi.00704-22"}},"subtitle":[],"editor":[{"given":"Susana","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,6,22]]},"references-count":66,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,6,22]]}},"alternative-id":["10.1128\/jvi.00704-22"],"URL":"https:\/\/doi.org\/10.1128\/jvi.00704-22","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,22]]},"assertion":[{"value":"2022-05-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00704-22"}}