{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:56:54Z","timestamp":1787320614738,"version":"build-2736575974"},"reference-count":59,"publisher":"American Society for Microbiology","issue":"16","license":[{"start":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T00:00:00Z","timestamp":1661299200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T00:00:00Z","timestamp":1661299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["108-2320-B-010-029-MY3"],"award-info":[{"award-number":["108-2320-B-010-029-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["110-2811-B-A49A-015"],"award-info":[{"award-number":["110-2811-B-A49A-015"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["109-2926-I-010-503"],"award-info":[{"award-number":["109-2926-I-010-503"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["111-2320-B-A49-030-MY3"],"award-info":[{"award-number":["111-2320-B-A49-030-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004737","name":"National Health Research Institutes","doi-asserted-by":"publisher","award":["NHRI-EX111-11125BI"],"award-info":[{"award-number":["NHRI-EX111-11125BI"]}],"id":[{"id":"10.13039\/501100004737","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["109-2221-E-010-018"],"award-info":[{"award-number":["109-2221-E-010-018"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004861","name":"Mackay Memorial Hospital","doi-asserted-by":"publisher","award":["MMH-CT-11106"],"award-info":[{"award-number":["MMH-CT-11106"]}],"id":[{"id":"10.13039\/501100004861","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2022,8,24]]},"abstract":"<jats:p>PEL is an aggressive and untreatable B-cell lymphoma caused by KSHV infection. Therefore, new therapeutic approaches for PEL need to be investigated.<\/jats:p>","DOI":"10.1128\/jvi.00755-22","type":"journal-article","created":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T14:40:26Z","timestamp":1659364826000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":9,"title":["SUMO Modification of Histone Demethylase KDM4A in Kaposi\u2019s Sarcoma-Associated Herpesvirus-Induced Primary Effusion Lymphoma"],"prefix":"10.1128","volume":"96","author":[{"given":"Wayne W.","family":"Yeh","sequence":"first","affiliation":[{"name":"Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"},{"name":"Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin-Quan","family":"Chen","sequence":"additional","affiliation":[{"name":"Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-Shan","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"},{"name":"Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung-Chih","family":"Hong","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sen","family":"Kao","sequence":"additional","affiliation":[{"name":"Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tze-Tze","family":"Liu","sequence":"additional","affiliation":[{"name":"Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4028-2375","authenticated-orcid":true,"given":"Ting-Wen","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"},{"name":"Center for Intelligent Drug Systems and Smart Bio-devices (IDS2B), National Yang Ming Chiao Tung University, Hsinchu, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lung","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, MacKay Children\u2019s Hospital and MacKay Memorial Hospital, Taipei, Taiwan"},{"name":"Department of Medicine, MacKay Medical College, New Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8665-5494","authenticated-orcid":true,"given":"Pei-Ching","family":"Chang","sequence":"additional","affiliation":[{"name":"Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan"},{"name":"Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan"},{"name":"Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-56352-2_4"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2011.03.003"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.24251"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2019-01-893339"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000071"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0000000000000334"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-08-373738"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S167392"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/hon.2372"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.71.1.314-324.1997"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3569"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.00850"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000935"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003813"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001013"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02665-13"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI64503"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01785-20"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/21.11.2602"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.2.690"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.13.6245-6248.2001"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.74.24.11977-11982.2000"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01459-21"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2012.118"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006216"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005051"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02485-10"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201902584R"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1042\/BST20191219"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2405081"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06134-z"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-12-3791"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V94.8.2871"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.6.2069.h8002069_2069_2073"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2012.00073"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003336"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007267"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700438"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb1273"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cancergen.2014.11.001"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.750315"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-20-3317"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2022.109806"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-021-00657-0"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2019.10.006"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI30945"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01742-10"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.3109\/07357907.2012.657813"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-1624-z"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.06240-11"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-05-220111"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-10-388538"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI59266"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2021.2003533"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2009.117"},{"key":"e_1_3_3_57_2","first-page":"709","article-title":"Inhibition of interleukin 10 by rituximab results in down-regulation of bcl-2 and sensitization of B-cell non-Hodgkin's lymphoma to apoptosis","volume":"7","author":"Alas S","year":"2001","unstructured":"Alas S, Emmanouilides C, Bonavida B. 2001. Inhibition of interleukin 10 by rituximab results in down-regulation of bcl-2 and sensitization of B-cell non-Hodgkin's lymphoma to apoptosis. Clin Cancer Res 7:709\u2013723.","journal-title":"Clin Cancer Res"},{"key":"e_1_3_3_58_2","first-page":"5137","article-title":"Rituximab inactivates signal transducer and activation of transcription 3 (STAT3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine\/paracrine loop and results in down-regulation of Bcl-2 and sensitization to cytotoxic drugs","volume":"61","author":"Alas S","year":"2001","unstructured":"Alas S, Bonavida B. 2001. Rituximab inactivates signal transducer and activation of transcription 3 (STAT3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine\/paracrine loop and results in down-regulation of Bcl-2 and sensitization to cytotoxic drugs. Cancer Res 61:5137\u20135144.","journal-title":"Cancer Res"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2711"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm1492"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00755-22","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00755-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T09:06:01Z","timestamp":1661331961000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jvi.00755-22"}},"subtitle":[],"editor":[{"given":"Jae U.","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,8,24]]},"references-count":59,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2022,8,24]]}},"alternative-id":["10.1128\/jvi.00755-22"],"URL":"https:\/\/doi.org\/10.1128\/jvi.00755-22","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,24]]},"assertion":[{"value":"2022-05-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00755-22"}}