{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T16:17:14Z","timestamp":1793117834389,"version":"4.5.0"},"reference-count":150,"publisher":"American Society for Microbiology","issue":"21","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["HHS N272201400007C"],"award-info":[{"award-number":["HHS N272201400007C"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"HHS | NIH | National Institute on Aging","doi-asserted-by":"publisher","award":["U54AG062333"],"award-info":[{"award-number":["U54AG062333"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>Influenza is a global public health problem. Current seasonal influenza vaccines have highly variable efficacy, and thus attempts to develop broadly protective universal influenza vaccines with durable protection are under way. While much attention is given to the virus-related factors contributing to inconsistent vaccine responses, host-associated factors are often neglected.<\/jats:p>","DOI":"10.1128\/jvi.00797-19","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T07:26:01Z","timestamp":1565162761000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":117,"title":["Host Factors Impact Vaccine Efficacy: Implications for Seasonal and Universal Influenza Vaccine Programs"],"prefix":"10.1128","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4494-8608","authenticated-orcid":false,"given":"Santosh","family":"Dhakal","sequence":"first","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabra L.","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA"},{"name":"Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","volume-title":"Influenza (seasonal) fact sheet","author":"WHO","year":"2018","unstructured":"WHO. 2018. Influenza (seasonal) fact sheet. World Health Organization, Geneva, Switzerland. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/influenza-(seasonal). Accessed 5 May 2019."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-018-0002-y"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0904322"},{"key":"e_1_3_2_5_2","volume-title":"Disease burden of influenza fact sheet","author":"CDC","year":"2018","unstructured":"CDC. 2018. Disease burden of influenza fact sheet. Centers for Disease Control and Prevention, Atlanta. GA. https:\/\/www.cdc.gov\/flu\/about\/burden\/index.html. Accessed 31 December 2018."},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy103"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1119945109"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2018.06.016"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw816"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6722a5"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2016-312165"},{"key":"e_1_3_2_12_2","volume-title":"Estimated influenza illnesses, medical visits, and hospitalizations averted by vaccination in the United States","author":"CDC","year":"2018","unstructured":"CDC. 2018. Estimated influenza illnesses, medical visits, and hospitalizations averted by vaccination in the United States. Centers for Disease Control and Prevention, Atlanta, GA. https:\/\/www.cdc.gov\/flu\/about\/disease\/2016-17.htm. Accessed 31 December 2018."},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-1711"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400022610"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1017\/s0022172400053158"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1712377114"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2013.07.007"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2017.1240041"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciq015"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2017.11.005"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1086\/507309"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2017.1377376"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/pit053"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70295-X"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.06.064"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2005.08.105"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(16)00129-8"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2017.22.44.17-00306"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1586\/erv.12.66"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2017.1285475"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2015.1123357"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1086\/516788"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0901022"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu573"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.11.012"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxr123"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.10.023"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002920"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI57834"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.04.023"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004794"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1617959114"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv202"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.24.12182-12187.2001"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.168.11.5893"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.173.1.673"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1302503"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.01.136"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.12.029"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0023698"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00784"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2019.01.002"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1315727"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2013.07.059"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12742"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0150425"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41541-019-0124-6"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.18632\/aging.101105"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.9254"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00295"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.02.012"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0153195"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-100616-060718"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2008.513"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1321060111"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2005.11.057"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1086\/599790"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.07.026"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1086\/656601"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1017\/s095026880005874x"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(02)00181-0"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2007.07.015"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofy211"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.09.110"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.09.006"},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biologicals.2018.01.007"},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1805268115"},{"key":"e_1_3_2_78_2","doi-asserted-by":"publisher","DOI":"10.3109\/08916934.2014.993027"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/814598"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.01.080"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2017.08.003"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00396-10"},{"key":"e_1_3_2_83_2","first-page":"572","article-title":"On the doctrine of original antigenic sin","volume":"104","author":"Francis T","year":"1960","unstructured":"Francis T, Jr. 1960. On the doctrine of original antigenic sin. Proc Am Philos Soc 104:572\u2013578.","journal-title":"Proc Am Philos Soc"},{"key":"e_1_3_2_84_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002802"},{"key":"e_1_3_2_85_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3006637"},{"key":"e_1_3_2_86_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-015-0239-y"},{"key":"e_1_3_2_87_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2013.12.008"},{"key":"e_1_3_2_88_2","doi-asserted-by":"crossref","first-page":"177","DOI":"10.4049\/jimmunol.97.2.177","article-title":"Original antigenic sin in ferrets: the response to sequential infections with influenza viruses","volume":"97","author":"Webster RG","year":"1966","unstructured":"Webster RG. 1966. Original antigenic sin in ferrets: the response to sequential infections with influenza viruses. J Immunol 97:177\u2013183.","journal-title":"J Immunol"},{"key":"e_1_3_2_89_2","first-page":"183","article-title":"Original antigenic sin to influenza in rats","volume":"46","author":"Angelova LA","year":"1982","unstructured":"Angelova LA, Shvartsman Ya S. 1982. Original antigenic sin to influenza in rats. Immunology 46:183\u2013188.","journal-title":"Immunology"},{"key":"e_1_3_2_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.11.077"},{"key":"e_1_3_2_91_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1801149"},{"key":"e_1_3_2_92_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2018.05.010"},{"key":"e_1_3_2_93_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1409171111"},{"key":"e_1_3_2_94_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix634"},{"key":"e_1_3_2_95_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix526"},{"key":"e_1_3_2_96_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0912458109"},{"key":"e_1_3_2_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.12.011"},{"key":"e_1_3_2_98_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1186430"},{"key":"e_1_3_2_99_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1324197111"},{"key":"e_1_3_2_100_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aag1322"},{"key":"e_1_3_2_101_2","doi-asserted-by":"publisher","DOI":"10.2147\/RRB.S80652"},{"key":"e_1_3_2_102_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aan2946"},{"key":"e_1_3_2_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.12.012"},{"key":"e_1_3_2_104_2","doi-asserted-by":"publisher","DOI":"10.1177\/2515135519826481"},{"key":"e_1_3_2_105_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318244ed20"},{"key":"e_1_3_2_106_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv138"},{"key":"e_1_3_2_107_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.10.2.184-187.1979"},{"key":"e_1_3_2_108_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30252-9"},{"key":"e_1_3_2_109_2","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2016.1192473"},{"key":"e_1_3_2_110_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0708630"},{"key":"e_1_3_2_111_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-016-0482-1"},{"key":"e_1_3_2_112_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.04.039"},{"key":"e_1_3_2_113_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.06.069"},{"key":"e_1_3_2_114_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1815325"},{"key":"e_1_3_2_115_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00654-11"},{"key":"e_1_3_2_116_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006757"},{"key":"e_1_3_2_117_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.64.3.1370-1374.1990"},{"key":"e_1_3_2_118_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.02.016"},{"key":"e_1_3_2_119_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1583"},{"key":"e_1_3_2_120_2","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2017.131"},{"key":"e_1_3_2_121_2","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2011.208"},{"key":"e_1_3_2_122_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001029"},{"key":"e_1_3_2_123_2","doi-asserted-by":"publisher","DOI":"10.4161\/hv.28332"},{"key":"e_1_3_2_124_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01144-16"},{"key":"e_1_3_2_125_2","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/4095789"},{"key":"e_1_3_2_126_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.03.011"},{"key":"e_1_3_2_127_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2012.04.011"},{"key":"e_1_3_2_128_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1019378108"},{"key":"e_1_3_2_129_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00284-013-0380-z"},{"key":"e_1_3_2_130_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2011.11.004"},{"key":"e_1_3_2_131_2","doi-asserted-by":"publisher","DOI":"10.12938\/bmfh.16-010"},{"key":"e_1_3_2_132_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2015.09.005"},{"key":"e_1_3_2_133_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2016.11.025"},{"key":"e_1_3_2_134_2","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451100420X"},{"key":"e_1_3_2_135_2","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2010.289"},{"key":"e_1_3_2_136_2","first-page":"504","article-title":"Lactobacillus plantarum CECT7315 and CECT7316 stimulate immunoglobulin production after influenza vaccination in elderly","volume":"27","author":"Bosch M","year":"2012","unstructured":"Bosch M, Mendez M, Perez M, Farran A, Fuentes MC, Cune J. 2012. Lactobacillus plantarum CECT7315 and CECT7316 stimulate immunoglobulin production after influenza vaccination in elderly. Nutr Hosp 27:504\u2013509.","journal-title":"Nutr Hosp"},{"key":"e_1_3_2_137_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12474"},{"key":"e_1_3_2_138_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2067"},{"key":"e_1_3_2_139_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2014.08.009"},{"key":"e_1_3_2_140_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.07.065"},{"key":"e_1_3_2_141_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268818002832"},{"key":"e_1_3_2_142_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2018.06.070"},{"key":"e_1_3_2_143_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-virology-031413-085537"},{"key":"e_1_3_2_144_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.00299"},{"key":"e_1_3_2_145_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071376"},{"key":"e_1_3_2_146_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep20842"},{"key":"e_1_3_2_147_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-018-0718-5"},{"key":"e_1_3_2_148_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20080521"},{"key":"e_1_3_2_149_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042192-200107000-00008"},{"key":"e_1_3_2_150_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5122(00)00180-8"},{"key":"e_1_3_2_151_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0149045"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.00797-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.00797-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T18:09:29Z","timestamp":1695060569000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JVI.00797-19"}},"subtitle":[],"editor":[{"given":"Carolyn B.","family":"Coyne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":150,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1128\/JVI.00797-19"],"URL":"https:\/\/doi.org\/10.1128\/jvi.00797-19","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"2019-10-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00797-19"}}