{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:25:27Z","timestamp":1790094327520,"version":"4.0.1"},"reference-count":76,"publisher":"American Society for Microbiology","issue":"18","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["096670\/Z\/11\/Z"],"award-info":[{"award-number":["096670\/Z\/11\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["104918\/Z\/14\/Z"],"award-info":[{"award-number":["104918\/Z\/14\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2022,9,28]]},"abstract":"<jats:p>Tick-borne encephalitis virus (TBEV) is an emerging virus of the flavivirus family that is spread by ticks and causes neurological disease of various severity. No specific therapeutic treatments are available for TBE, and control in areas of endemicity is limited to vaccination.<\/jats:p>","DOI":"10.1128\/jvi.00818-22","type":"journal-article","created":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T13:00:48Z","timestamp":1663074048000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["Identification of Host Factors Differentially Induced by Clinically Diverse Strains of Tick-Borne Encephalitis Virus"],"prefix":"10.1128","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2906-5513","authenticated-orcid":true,"given":"Niluka","family":"Goonawardane","sequence":"first","affiliation":[{"name":"School of Biological Sciences, University of Reading, Reading, United Kingdom"},{"name":"School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Upstone","sequence":"additional","affiliation":[{"name":"School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9821-1003","authenticated-orcid":true,"given":"Mark","family":"Harris","sequence":"additional","affiliation":[{"name":"School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian M.","family":"Jones","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, University of Reading, Reading, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000672"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050077"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.11.2067"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007295"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2019.01.014"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1603.081364"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/v12020247"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2019.24.47.1900658"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2601.191085"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2017.09.014"},{"key":"e_1_3_3_12_2","doi-asserted-by":"crossref","unstructured":"Kutschera LS Wolfinger MT. 2022. Evolutionary traits of tick-borne encephalitis virus: pervasive non-coding RNA structure conservation and molecular epidemiology. bioRxiv. 10.1101\/2021.12.16.473019.","DOI":"10.1101\/2021.12.16.473019"},{"key":"e_1_3_3_13_2","first-page":"13","article-title":"Genotypes 4 and 5 of the tick-borne encephalitis virus: features of the genome structure and possible scenario for its formation","volume":"57","author":"Demina TV","year":"2012","unstructured":"Demina TV, Dzhioev IP, Kozlova IV, Verkhozina MM, Tkachev SE, Doroshchenko EK, Lisak OV, Paramonov AI, Zlobin VI. 2012. Genotypes 4 and 5 of the tick-borne encephalitis virus: features of the genome structure and possible scenario for its formation. Vopr Virusol 57:13\u201319.","journal-title":"Vopr Virusol"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41426-018-0081-6"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21765"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.77.1.25-36.2003"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1997.8622"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0168-1702(94)90024-8"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0065-3527(03)61008-0"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000755"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3527(03)59002-9"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1928"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M607273200"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047912"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03456-12"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00176-10"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep10745"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000853"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1701507"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2011.08.004"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.05.040"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0081214"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.20.12828-12839.2005"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02714-05"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2007.01076.x"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2010.10.007"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2020.1745094"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12250-020-00208-3"},{"key":"e_1_3_3_39_2","first-page":"473","article-title":"Characteristics of long-term persisting strains of tick-borne encephalitis virus in different forms of the chronic process in animals","volume":"27","author":"Frolova TV","year":"1982","unstructured":"Frolova TV, Pogodina VV, Frolova MP, Karmysheva VI. 1982. Characteristics of long-term persisting strains of tick-borne encephalitis virus in different forms of the chronic process in animals. Vopr Virusol 27:473\u2013479. (In Russian.)","journal-title":"Vopr Virusol"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0166-0934(98)00130-x"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-77-5-1035"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1386-6532(02)00168-3"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158105"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1207339"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/bs.mie.2014.10.044"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-10-8727-1_12"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2008.04.035"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2009.05.016"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2016.11.031"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02932-15"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.71.2.1497-1505.1997"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1934678100"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep39265"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2009.03.007"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.3390\/v6072826"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-015-1210-x"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03736-13"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2017.02.006"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2017.11.008"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.3390\/v12101059"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2701"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a008656"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60238-X"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.2807\/ese.13.26.18916-en"},{"key":"e_1_3_3_65_2","unstructured":"European Centre for Disease Prevention and Control. 2015. Factsheet on tick-borne encephalitis for healthcare professionals. European Centre for Disease Prevention and Control Stockholm Sweden."},{"key":"e_1_3_3_66_2","first-page":"129","volume-title":"Methods in enzymology.","author":"Strack RL","year":"2015","unstructured":"Strack RL, Jaffrey SR. 2015. Live-cell imaging of mammalian RNAs with Spinach2, p 129\u2013146. In Burke-Aguero DH (ed), Methods in enzymology. Academic Press, San Diego, CA."},{"key":"e_1_3_3_67_2","doi-asserted-by":"crossref","unstructured":"Goonawardane N Upstone L Harris M Jones IM. 2021. Identification of host antiviral genes differentially induced by clinically diverse strains of Tick-Borne encephalitis virus. bioRxiv. 10.1101\/2021.02.23.432617.","DOI":"10.1101\/2021.02.23.432617"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2017.04.012"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1704454114"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09118"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06287"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-018-0240-5"},{"key":"e_1_3_3_73_2","volume-title":"Infectious diseases related to travel TBE.","author":"Fischer M","year":"2016","unstructured":"Fischer M, Rabe I, R P. 2016. Infectious diseases related to travel TBE. CDC, Atlanta, GA."},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1318"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.31"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2818.2006.01706.x"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006834"}],"updated-by":[{"DOI":"10.1128\/jvi.01531-22","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T00:00:00Z","timestamp":1666051200000}}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00818-22","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jvi.00818-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T13:05:24Z","timestamp":1664370324000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jvi.00818-22"}},"subtitle":[],"editor":[{"given":"Mark T.","family":"Heise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,9,28]]},"references-count":76,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2022,9,28]]}},"alternative-id":["10.1128\/jvi.00818-22"],"URL":"https:\/\/doi.org\/10.1128\/jvi.00818-22","relation":{"correction":[{"id-type":"doi","id":"10.1128\/jvi.01531-22","asserted-by":"object"}]},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,28]]},"assertion":[{"value":"2022-05-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00818-22"}}