{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:29:43Z","timestamp":1792531783547,"version":"4.5.0"},"reference-count":35,"publisher":"American Society for Microbiology","issue":"23","license":[{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We show that poliovirus (PV) infection induces an increase in cytosolic calcium (Ca\n            <jats:sup>2+<\/jats:sup>\n            ) concentration in neuroblastoma IMR5 cells, at least partly through Ca\n            <jats:sup>2+<\/jats:sup>\n            release from the endoplasmic reticulum lumen via the inositol 1,4,5-triphosphate receptor (IP\n            <jats:sub>3<\/jats:sub>\n            R) and ryanodine receptor (RyR) channels. This leads to Ca\n            <jats:sup>2+<\/jats:sup>\n            accumulation in mitochondria through the mitochondrial Ca\n            <jats:sup>2+<\/jats:sup>\n            uniporter and the voltage-dependent anion channel (VDAC). This increase in mitochondrial Ca\n            <jats:sup>2+<\/jats:sup>\n            concentration in PV-infected cells leads to mitochondrial dysfunction and apoptosis.\n          <\/jats:p>","DOI":"10.1128\/jvi.00994-10","type":"journal-article","created":{"date-parts":[[2010,9,23]],"date-time":"2010-09-23T04:30:04Z","timestamp":1285216204000},"page":"12226-12235","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":61,"title":["Calcium Flux between the Endoplasmic Reticulum and Mitochondrion Contributes to Poliovirus-Induced Apoptosis"],"prefix":"10.1128","volume":"84","author":[{"given":"Cynthia","family":"Brisac","sequence":"first","affiliation":[{"name":"Institut Pasteur, Unite\u0301 de Biologie des Virus Ente\u0301riques, 25 rue du Dr Roux, 75015 Paris, France"},{"name":"INSERM U994, Paris, France"},{"name":"Universite\u0301 Versailles Saint-Quentin, Versailles, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franc\u0327ois","family":"Te\u0301oule\u0301","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unite\u0301 de Biologie des Virus Ente\u0301riques, 25 rue du Dr Roux, 75015 Paris, France"},{"name":"INSERM U994, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Autret","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unite\u0301 de Biologie des Virus Ente\u0301riques, 25 rue du Dr Roux, 75015 Paris, France"},{"name":"INSERM U994, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Pelletier","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unite\u0301 de Biologie des Virus Ente\u0301riques, 25 rue du Dr Roux, 75015 Paris, France"},{"name":"INSERM U994, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Colbe\u0300re-Garapin","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unite\u0301 de Biologie des Virus Ente\u0301riques, 25 rue du Dr Roux, 75015 Paris, France"},{"name":"INSERM U994, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Brenner","sequence":"additional","affiliation":[{"name":"Universite\u0301 Versailles Saint-Quentin, Versailles, France"},{"name":"INSERM U769, Signalisation et Physiopathologie Cardiaque, Cha\u0302tenay Malabry, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Lemaire","sequence":"additional","affiliation":[{"name":"Universite\u0301 Versailles Saint-Quentin, Versailles, France"},{"name":"INSERM U769, Signalisation et Physiopathologie Cardiaque, Cha\u0302tenay Malabry, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Blondel","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unite\u0301 de Biologie des Virus Ente\u0301riques, 25 rue du Dr Roux, 75015 Paris, France"},{"name":"INSERM U994, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","first-page":"40434","volume":"277","year":"2002","unstructured":"Agirre, A., A. 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