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The importance of bats as natural hosts for several important viral zoonoses, including Ebola, Marburg, Nipah, Hendra, and rabies viruses and severe acute respiratory syndrome-coronavirus (SARS-CoV), has been established; however, the large viral population diversity (virome) of bats has been partially determined for only a few of the \u223c1,200 bat species. To assess the virome of North American bats, we collected fecal, oral, urine, and tissue samples from individual bats captured at an abandoned railroad tunnel in Maryland that is cohabitated by 7 to 10 different bat species. Here, we present preliminary characterization of the virome of three common North American bat species, including big brown bats (\n                    <jats:italic>Eptesicus fuscus<\/jats:italic>\n                    ), tricolored bats (\n                    <jats:italic>Perimyotis subflavus<\/jats:italic>\n                    ), and little brown myotis (\n                    <jats:italic>Myotis lucifugus<\/jats:italic>\n                    ). In samples derived from these bats, we identified viral sequences that were similar to at least three novel group 1 CoVs, large numbers of insect and plant virus sequences, and nearly full-length genomic sequences of two novel bacteriophages. These observations suggest that bats encounter and disseminate a large assortment of viruses capable of infecting many different animals, insects, and plants in nature.\n                  <\/jats:p>","DOI":"10.1128\/jvi.01255-10","type":"journal-article","created":{"date-parts":[[2010,10,6]],"date-time":"2010-10-06T22:06:33Z","timestamp":1286402793000},"page":"13004-13018","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":200,"title":["Metagenomic Analysis of the Viromes of Three North American Bat Species: Viral Diversity among Different Bat Species That Share a Common Habitat"],"prefix":"10.1128","volume":"84","author":[{"given":"Eric F.","family":"Donaldson","sequence":"first","affiliation":[{"name":"Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimee N.","family":"Haskew","sequence":"additional","affiliation":[{"name":"University of Maryland Center for Environmental Science, Appalachian Laboratory, Frostburg, Maryland 21532"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Edward","family":"Gates","sequence":"additional","affiliation":[{"name":"University of Maryland Center for Environmental Science, Appalachian Laboratory, Frostburg, Maryland 21532"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Huynh","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clea J.","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Oakwood University, Huntsville, Alabama 35896"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew B.","family":"Frieman","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of Maryland at Baltimore, Baltimore, Maryland 21201"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.211424698"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/512196"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504666102"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0907.030004"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2009.10.007"},{"key":"e_1_3_2_7_2","unstructured":"Bats of America 1969"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0808116105"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn723"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1413-86702008000600003"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.2144\/000112019"},{"key":"e_1_3_2_12_2","unstructured":"Plant viruses online: descriptions and lists from the VIDE database 1996"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-42.2.455"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00017-06"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-10-421"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11262-004-5624-3"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1412.080642"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1092002"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.83605-0"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.82203-0"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2010.01.023"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01285-08"},{"key":"e_1_3_2_23_2","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1111\/j.1365-294X.2007.03616.x","volume":"17","year":"2008","unstructured":"Degnan, P. 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