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Studies addressing the ability of rAAV to induce protective T cell responses, however, are scarce. Notably, the potential to induce a tissue-resident memory T cell response has never been described for rAAV vectors, strongly limiting further interest for their use as vaccine carriers. Using a model rAAV2\/1 vaccine delivered to the skin, our study demonstrated that rAAV vectors can induce bona fide skin resident T\n            <jats:sub>RM<\/jats:sub>\n            and provides additional clues regarding the cellular mechanisms underlying this process. These results will help widen the field of rAAV applications.\n          <\/jats:p>","DOI":"10.1128\/jvi.01334-18","type":"journal-article","created":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T10:32:21Z","timestamp":1544610741000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":9,"title":["Cross-Presentation of Skin-Targeted Recombinant Adeno-associated Virus 2\/1 Transgene Induces Potent Resident Memory CD8\n            <sup>+<\/sup>\n            T Cell Responses"],"prefix":"10.1128","volume":"93","author":[{"given":"David-Alexandre","family":"Gross","sequence":"first","affiliation":[{"name":"Institut Necker Enfants Malades (INEM), INSERM U1151, CNRS UMR8253, Facult\u00e9 de M\u00e9decine, Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, 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