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The current antiviral agents used to treat HCMV infections are prone to resistance and can be toxic to patients, and there is no current vaccine against HCMV available. The data in this report will lead to a better understanding of how essential HCMV envelope glycoproteins function during infection of biologically important cell types and will have significant implications for understanding HCMV pathogenesis for developing new therapeutics.<\/jats:p>","DOI":"10.1128\/jvi.01336-18","type":"journal-article","created":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T07:14:21Z","timestamp":1534144461000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":55,"title":["The Human Cytomegalovirus Trimer and Pentamer Promote Sequential Steps in Entry into Epithelial and Endothelial Cells at Cell Surfaces and Endosomes"],"prefix":"10.1128","volume":"92","author":[{"given":"Jing","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Structural Biology, Stanford University School of Medicine, Stanford, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ted S.","family":"Jardetzky","sequence":"additional","affiliation":[{"name":"Department of Structural Biology, Stanford University School of Medicine, Stanford, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea L.","family":"Chin","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Oregon Health &amp; Science University, Portland, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Oregon Health &amp; Science University, Portland, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam L.","family":"Vanarsdall","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Oregon Health &amp; Science University, Portland, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","first-page":"1","volume-title":"Cytomegaloviruses: molecular biology and immunology","author":"Britt W","year":"2006","unstructured":"Britt W. 2006. 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