{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T18:28:13Z","timestamp":1791052093683,"version":"4.1.0"},"reference-count":24,"publisher":"American Society for Microbiology","issue":"19","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The transfer of T cell receptor (TCR) genes by viral vectors represents a promising technique to generate antigen-specific T cells for adoptive immunotherapy. TCR-transduced T cells specific for infectious pathogens have been described, but their protective function\n            <jats:italic>in vivo<\/jats:italic>\n            has not yet been examined. Here, we demonstrate that CD8 T cells transduced with the P14 TCR specific for the gp33 epitope of lymphocytic choriomeningitis virus exhibit protective activities in both viral and bacterial infection models in mice.\n          <\/jats:p>","DOI":"10.1128\/jvi.01472-12","type":"journal-article","created":{"date-parts":[[2012,7,12]],"date-time":"2012-07-12T04:53:58Z","timestamp":1342068838000},"page":"10866-10869","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["Protective Capacity of Virus-Specific T Cell Receptor-Transduced CD8 T Cells\n            <i>In Vivo<\/i>"],"prefix":"10.1128","volume":"86","author":[{"given":"Katja","family":"Mueller","sequence":"first","affiliation":[{"name":"Institute of Medical Microbiology and Hygiene, Department of Immunology, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"von M\u00e4ssenhausen","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology and Hygiene, Department of Immunology, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Aichele","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology and Hygiene, Department of Immunology, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilian","family":"St\u00e4rck","sequence":"additional","affiliation":[{"name":"Max Delbr\u00fcck Center for Molecular Medicine, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Leisegang","sequence":"additional","affiliation":[{"name":"Max Delbr\u00fcck Center for Molecular Medicine, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Uckert","sequence":"additional","affiliation":[{"name":"Max 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